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Medical and Biomedical Sciences

Principal Investigator: John Aris
Field of Research: Aging
Phone Number: 392-1873
E-mail: johnaris@ufl.edu
Project Description: Molecular and Cellular Basis of Aging Our laboratory is interested in the molecular and cellular basis for aging. There are a number of mechanisms at the molecular and cellular levels that contribute to the aging process, including, but not limited to: (1) genomic instability; (2) reactive oxygen species (ROS) damage; and (3) impaired repair pathways. Genomic instability includes loss and rearrangement of genetic information in cells. For example, in baker’s yeast, recombination within the repetitive ribosomal DNA (rDNA) locus give rise to extrachromosomal rDNA circles (ERCs) that are linked to the aging process. We are currently interested in understanding the mechanism(s) by which ERCs reduce life span. We use yeast as an experimental system because of the ease of using various approaches in biochemistry, cell biology, genetics, and molecular biology. Our overall goal is to pursue mechanisms that regulate life span in yeast cells and extend these studies to higher cells types in order to better understand general mechanisms that influence aging at the molecular and cellular levels.
Requirements: Basic knowledge of biology and genetics. Strong commitment to, and adequate time for, research (minimum one semester). Upper classmen (junior/senior) preferred, but exceptions can be made.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: John Aris
Field of Research: Aging
Phone Number: 392-1873
E-mail: johnaris@ufl.edu
Project Description: Molecular and Cellular Basis of Aging -- Our laboratory is interested in the molecular and cellular basis for aging. There are a number of mechanisms at the molecular and cellular levels that contribute to the aging process, including, but not limited to: (1) genomic instability; (2) reactive oxygen species (ROS) damage; and (3) impaired repair pathways. Genomic instability includes loss and rearrangement of genetic information in cells. For example, in baker’s yeast, recombination within the repetitive ribosomal DNA (rDNA) locus give rise to extrachromosomal rDNA circles (ERCs) that are linked to the aging process. We are currently interested in understanding the mechanism(s) by which ERCs reduce life span. We use yeast as an experimental system because of the ease of using various approaches in biochemistry, cell biology, genetics, and molecular biology. Our overall goal is to pursue mechanisms that regulate life span in yeast cells and extend these studies to higher cells types in order to better understand general mechanisms that influence aging at the molecular and cellular levels.
Requirements: Basic knowledge of biology and genetics. Strong commitment to, and adequate time for, research (minimum one semester). Upper classmen (junior/senior) preferred, but exceptions can be made.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Roland Aud
Field of Research: Pain
Phone Number: 273-5343
E-mail: staudr@ufl.edu
Project Description: Pain is a complex experience and almost always requires acitvation of nociceptors. However, in many pain syndromes such activation is not readily detectable. Low back pain and fibromyalgia are such pain disorders. This research project will examine the role of tonic nociceptive input on chronic pain in patients with fibromyalgia syndrome. Age/sex matched participants will be used as normal controls. Tonic pain will be induced by muscle stimulation and reduced by muscle injection with a local anesthetic. Psychophysical testing of the skin and muscle via computerized thermal/mechanical probes will be used to examine the role of tonic mechanical stimulations on pain and pain processing. In a subsequent study the same manipulations will be used during functional magnetic resonance scans (fMRI) to characterize the pain related brain areas related to tonic impulse input.
Requirements:
Starting Date: 2005
Ending Date: open
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Shirley Baker
Field of Research: Invertebrate Ecology and Physiology
Phone Number: 392-9617 x264
E-mail: smbaker@ifas.ufl.edu
Project Description: The selected student will assist with various aspects of field and laboratory research related to the CLAMMRS Project. Projects this summer include 1) Measuring currents and spatial and temporal variability in environmental parameters (temperature, salinity, oxygen, etc.) at clam grow-out sites, 2) Completing physiological tolerance experiments in the lab, and 3) Measuring energy budgets of clams. We will provide the student with a variety of field and laboratory research experiences; the student will also be involved in projects on invasive invertebrates, bivalve feeding and bivalve genetics.
Requirements: Location: NW Gainesville, Millhopper Road (transportation required)
Starting Date: May 1, negotiable
Ending Date: negotiable
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Russel M. Bauer
Field of Research: Neuropsychology
Phone Number: 273-6455
E-mail: rbauer@phhp.ufl.edu
Project Description: Develop protocols for early detection of dementia
Requirements: some psychology background
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-3
Summer Positions: contact faculty mentor
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Russell M. Bauer
Field of Research: Neuropsychology
Phone Number: 273-6455
E-mail: rbauer@phhp.ufl.edu
Project Description: Evaluate cognitive effects of epilepsy and of surgical interventions for epilepsy relief.
Requirements: some psychology background
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-3
Summer Positions: contact faculty mentor
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Andrea Behrman
Field of Research: Physical Therapsy
Phone Number: 273-6116
E-mail: abehrman@phhp.ufl.edu
Project Description: The purpose of this study is to compare the effects of robotic- versus manually-assisted locomotor training on walking ability in adults with incomplete spinal cord injury. The purpose of a second study is to pilot a training protocol to improve the recovery of walking in persons post-stroke.
Requirements: Demonstrate initiative and is responsible. Basic computer skills. Background in psychology, biology, exercise science, biomechanics, or motor learning may be most appropriate. Availability during particular hours for training subjects, as well as a flexible schedule for working on data sets and video logs.
Starting Date: March, 2005
Ending Date: March, 2008
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Dr. Steve Borst
Field of Research: Pharmacology
Phone Number: 374-6114
E-mail: seborst@ufl.edu
Project Description: My lab is interested in studying the loss of muscle mass and strength that occurs as a part of the aging process and in testing strategies for reversing those losses. Age is accompanied by changes in the growth hormone and insulin pathways. We study the effects in aged rats of 1) growth hormone and related hormones, 2) antidiabetic agents and/or 3) exercise training. You will have the chance to learn exercise traning performance techniques, assays of hormones and mRNA, measurement of body composition and measurement of responses to insulin.
Requirements: Background in biological science and sufficient time to participate in a project.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1B
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Peggy Borum
Field of Research: Clinical Nutrition
Phone Number: 352-392-7553
E-mail: prb@ufl.edu
Project Description: There are positions available for undergraduate students with a desire to be involved in a meaningful research experience. These projects emphasize independent, critical and creative thinking. The research lab is composed of three research teams. The Gator Team works with children who are HIV positive. There are patient care concerns as well as gathering nutritional and body composition data for clinical studies. The Carnitine Team studies the long-chain fatty acid carrier, carnitine, by working with animal models and analyzing data gathered in both human and animal studies. The KetoGator Team works with children participating in Ketogenic Therapy for seizures, which is a dietary alternative to anticonvulsant medications. There is an emphasis on patient care and gathering data for clinical studies. Members of all three teams make up the InvestiGators. InvestiGators is a research-based honor society that provides students who are involved in intensive research a forum to practice good research procedure, share knowledge, and foster friendships (http://borum.ifas.ufl.edu/Investigators/). Undergraduate students with adequate commitment to the project have opportunities to be involved in either patient interaction or bench research. With time, there is a potential for leadership positions and personal thesis projects.
Requirements: Students must be willing to commit a minimum of 15-20 hours a week for a minimum of 1 year to the project and perform in a mature and professional manner.
Starting Date: Anytime
Ending Date: Anytime
Academic Year Positions: Flexible
Summer Positions: Flexible
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Dawn Bowers
Field of Research: Neuropsychology
Phone Number: 392-3450
E-mail: dbowers@hp.ufl.edu
Project Description: My lab focuses on the neuropsychology of emotion, memory, and higher order cognition in normals and patients with various neurologic and/or psychiatric disorders. This is a multidisciplinary laboratory in cognitive neuroscience/ clinical neuropsychology. We conduct studies across the lifespan(children to adults). Research methods vary from paper & pencil to more technologically complex (e.g., transcranial magnetic stimulation, psychophysiology, neuroimaging, priming, face digitizing, computerized tasks). Students get well-rounded research experience and the opportunity to learn more about graduate school or medical school. Most undergrads in my lab go on to graduate school (clinical psychology, neuroscience) or medical school. For more information, you can check out my lab's website at: www.hp.ufl.edu/cogneuro
Requirements: Some psychology and statistics are required; GPA of 3.4; curiosity and willingness to learn, attention to detail coupled with good people skills; Minimum of 3 credits per semester (8-10 hours/week), including one hour for weekly lab meetings. Committment of at least 2 semesters in desirable.
Starting Date: anytime
Ending Date: varies
Academic Year Positions: 1-3
Summer Positions: 1-3
Independent Study: Required
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Marc Branch
Field of Research: behavioral pharmacology
Phone Number: 392-0601 x205
E-mail: branch@ufl.edu
Project Description: Discovery and characterization of behavioral/experiential factors that determine whether an animal's behavior reveals tolerance or sensitization (or neither) in the face of repeated exposure to psychoactive drugs. Undergrad activities involve either behavioral observations, data-analysis, or both.
Requirements: Interest in behavior.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2 to 3
Summer Positions: 2 to 3
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Mark Brantly
Field of Research: Genetics/Cell Biology
Phone Number: 352-846-0752
E-mail: brantml@medicine.ufl.edu
Project Description: Identify novel mutations in the Alpha-1-antitrypsin gene (SERPINA1) using a combination of high resolutions DNA melting and DNA sequencing
Requirements: must have completed basic genetics courses and be available 20 hrs/week
Starting Date: 9/1/05
Ending Date: 8/30/06
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Mark Brantly
Field of Research: Genetics/Cell Biology
Phone Number: 352-846-0752
E-mail: brantml@medicine.ufl.edu
Project Description: Evaluate and map the unfolded protein response in cells expressing the a mutant form of alpha-1-antitrypsin (SERPINA1)
Requirements: must have complete basic cell biology courses
Starting Date: 9/1/05
Ending Date: 8/30/06
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Daniel Brazeau
Field of Research: Population biology/Genetics
Phone Number: 392-5016
E-mail: dbrazeau@biotech.ufl.edu
Project Description: The laboratory is part of the Molecular Services Core within the Interdisciplinary Center for Biotechnology Research at UF. The role of the BEECS Genetic Analysis Lab is to assist ecologists, and evolutionary and conservation biologists in taking advantage of the wide variety of molecular markers now available for field and laboratory studies. Projects include 1) population genetics of corals, scrub lizards, rattlesnakes, sea turtles, viscachas; 2) Paternity analysis in soft and stony corals, crickets, weaverbirds, mole salamanders; 3) Phylogenetic studies of rattlesnakes, striped newts, sirens, and 4) DNA Wildlife Forensics
Requirements: Basic knowledge of biology and a willingness to work in a lab
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Adriaan Bruijnzeel
Field of Research: Drug dependence
Phone Number: (352) 328-9793
E-mail: awbruijn@psychiatry.ufl.edu
Project Description: The aim of this project is to develop novel treatments for nicotine dependence. Abrupt cessation of tobacco smoking has been shown to induce depression and anxiety. It has been hypothesized that these symptons contribute to relapse. This projects focuses on the development of pharmacotherapies for the depressive-like signs of nicotine withdrawal using rodent intracranial self-stimulation. Abrupt cessation of nicotine administration has been shown to decrease the postive reinforcing effects of intracranial self-stimulation (i.e., deficit in brain reward function). This project will investigate the effects of novel drug treatments on the depressive-like signs of nicotine withdrawal.
Requirements: Projects are time consuming, but the student can learn numerous new techniques, including surgeries. This project is only suitable for students with a strong interest in preclinical biomedical research.
Starting Date: 08/18/05
Ending Date:
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Emilio Bruna
Field of Research: Ecology
Phone Number: 846-0634
E-mail: brunae@wec.ufl.edu
Project Description: We study (1) the diversity and abundance of invertebrates (especially ants) in local ecosystems, (2) plant-animal interactions, especially ant-plant protection mutualisms, and (3) the effect of human activities such as habitat fragmentation and the disruption of natural fire regimes on plant-animal interactions and plant population ecology. These projects involve field, lab, or computer work, (for example, sample collection, insect identification, field experiments, computer models, GIS analysis). There is the potential for future independent projects. For a description of the lab's projects see www.wec.ufl.edu/faculty/brunae.
Requirements: Depending on the project, previous training in ecology, entomology, GIS, matrix algebra, or MATLAB is helpful. However, no experience is necessary - all you need is an interest in ecology and a willingness to learn new things.
Starting Date: Anytime
Ending Date: 3 month commitment
Academic Year Positions: open
Summer Positions: open
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Michael Bubb, Assoc. Prof
Field of Research: Immunology/Cell Biology/Biophysics
Phone Number: (352) 392-4681
E-mail: bubbmr@medicine.ufl.edu
Project Description: Cells undergo programmed cell death or apoptosis as a normal physiologic or developmental response; abnormalities in this process result in significant pathology relevant to both the immune system and to the development of cancer. Our laboratory has been investigating the role of the actin cytoskeleton in apoptosis. This student project will entail the study of the mechanism by which apoptosis is induced when marine natural products alter the actin cytoskeleton. The student can expect to be included as an author of publications that include his or her results. A more complete description of our lab's research can be found at: http://www.medicine.ufl.edu/rheuma/bubb.shtml
Requirements: Please provide current college transcript. Background that includes laboratory coursework in molecular biology and/or cell biology and/or immunology would be helpful. Salary available for general laboratory maintenance responsibilities and activities.
Starting Date: Spring or Summer 2003-2004
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Michael Bubb, Assoc. Prof
Field of Research: Neuroscience/Cell Biology/Biophysics
Phone Number: (352) 392-4681
E-mail: bubbmr@medicine.ufl.edu
Project Description: Memory formation and retention require remodeling of neuronal architecture. Our laboratory investigates the role of the actin cytoskeleton in this remodeling process, which we believe is the structural basis for synaptic plasticity. This student project will entail the study of the mechanism by which actin-regulatory proteins control neuronal architecture at the level of the synapse. The student can expect to be included as an author of publication that include his or her results. A more complete description of our lab's research can be found at: http://www.medicine.ufl.edu/rheuma/bubb.shtml
Requirements: Please provide current college transcript. Background that include laboratory coursework in molecular biology and/or cell biology and/or biochemistry would be helpful. Salary available for general laboratory maintenance responsibilities and activities.
Starting Date: Spring or summer 2003-2004
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: George Burgess
Field of Research: Biology: Ichthyology
Phone Number: 392-2360
E-mail: gburgess@flmnh.ufl.edu
Project Description: The International Shark Attack File is a compilation of all known shark attacks that is administered by the American Elasmobranch Society, a professional organization comprised of international workers studying sharks, skates and rays, and the Florida Museum of Natural History. The File is utilized by biological researchers and research physicians; access to the data is granted only after careful screening on a case-by-case basis. Access by the press and general public is strictly forbidden since much information is considered privileged. Many of the data in the File originate from the voluntary submissions of numerous cooperating scientists who serve worldwide as regional observers. Regional observers forward investigations of attacks in their areas for integration into the File. Data submitted to the File is screened, coded and computerized. Hard copy documentation, including original notes, press clippings, photographs, audio/video tapes, and medical/autopsy reports, is permanently archived. More than 2,700 individual investigations are currently housed in the International Shark Attack File, covering the period from mid-1500's to present. Requests for summary information and non-privileged data are made to the File's director. Selected students may utilize the database, under supervision of the director, to produce honors or independent studies OR they may work as volunteers in ongoing research projects.
Requirements: Serious students may contact George H. Burgess for an interview. Normally only upper division (junior or senior) students majoring in a biological science are considered, but exceptions may be made.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 3
Independent Study: Required
Work Study: Available
Salary: Not Available
Volunteer: Required

Principal Investigator: George Burgess
Field of Research: Biology: Ichthyology
Phone Number: 392-2360
E-mail: gburgess@flmnh.ufl.edu
Project Description: The ichthyological WebPages of the Florida Museum of Natural History has proven to be an extremely popular site among World Wide Web users. The shark and conservation sections are particularly well utilized. It is our goal to continually upgrade the site with distance learning material aimed at a variety of user groups, including secondary school students, recreational anglers, aquarists, and lay conservationists. We are happy to accept qualified students interested in biology, secondary education, and computers to participate development of educational ichthyological WebPages material and placement aboard our web site.
Requirements: Serious students may contact George H. Burgess for an interview. Normally only upper division (junior or senior) students majoring in a biological science, secondary shool education, or a computer field are considered, but exceptions may be made.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 3
Independent Study: Required
Work Study: Available
Salary: Not Available
Volunteer: Required

Principal Investigator: George Burgess
Field of Research: Biology: Ichthyology
Phone Number: 392-2360
E-mail: gburgess@flmnh.ufl.edu or apiercy@flmnh.ufl.edu
Project Description: The Florida Program for Shark Research at the Florida Museum of Natural History currently is studying life history attributes of several species of sharks. We are looking for volunteers/independent study students available at a minimum of 6 hrs per week. Duties will include preparing shark reproductive tissues for histological studies, vertebrae for age and growth analyses, and shark jaws for tooth morphology studies. Experience with sharks is not required and students will be trained in the necessary skills. This is a multiyear study and volunteers may subsequently become eligible for part-time employment. Chances for students to earn academic credit through Independent Study and/or the University Scholars program will be addressed on an individual basis. We are looking for motivated students.
Requirements: Serious students may contact George H. Burgess or Andrew Piercy for an interview. Normally upper division (junior or senior) students majoring in a biological science are most highly considered, but highly motivated underclass students are encouraged to apply.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 3
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Robert Burne
Field of Research: Microbiology/Molecular Biology
Phone Number: 392-4370
E-mail: rburne@dental.ufl.edu
Project Description: Molecular genetic aspects of microbial biofilm formation. Biofilms are adherent populations of microbes imbedded in a polymer matrix and adhering to a surface. Biofilm diseases are highly prevalent in humans and eradication of biofilms is a major challenge. We are using a Functional Genomics approach to identify genes that are essential for the formation of pathogenic biofilms by bacteria. Using genome sequence information and DNA microarrays, we have identified a variety of genes of as-yet-unknown function that are essential for maturation of biofilms and tolerance of environmental stress. This project involves a combination of recombinant DNA methodology, biochemistry, physiology and microbiology to understand how bacteria form structurally complex biofilms and to identify new targets for combating infectious agents.
Requirements: Courses in microbiology and molecular genetics are desirable.
Starting Date: Flexible
Ending Date: Flexible
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Marian L. Buszko
Field of Research: Biomedical
Phone Number: (352) 392-7203
E-mail: marian@ufl.edu
Project Description: In-vivo NMR studies of gene regulation and/or metabolic pathways. The work may involve genetic engineering to explore metabolic potential in bacteria and the effects of extreme environments. In-vivo NMR experiments will be conducted using the unique, Web-operated instrument developed at the IFAS NMR Laboratory and available at the address http://m110.ifas.ufl.edu
Requirements: Microbiology or related major
Starting Date: 5/1/98
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Veronika Butterweck
Field of Research: Herbal Medicines
Phone Number: 352-846-2470
E-mail: butterwk@cop.ufl.edu
Project Description: Grapefruit juice (GFJ), a beverage consumed in large quantities by many, contains compounds with a wide range of beneficial properties including anti-inflammatory and anti-tumor activity, inhibition of blood clots and strong antioxidant activity. However, unlike other citrus fruit juices, grapefruit juice interacts with a variety of prescription medications, raising the potential for concern. The project is designed to identify compounds from GFJ that might be responsible for the interactions. The project includes analytical work (e.g. HPLC analysis of compounds) and cell culture models
Requirements: Research skills, willingness to work in a team
Starting Date: 09/01/2005
Ending Date: 08/31/2007
Academic Year Positions: 0
Summer Positions: 2
Independent Study: Not Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Brian Cain
Field of Research: Biochemistry and Molecular Biology
Phone Number: 392-6473
E-mail: bcain@biochem.med.ufl.edu
Project Description: The two major areas of research in the laboratory focus on ion translocating ATPases. One project suitable for undergraduate chemistry and microbiology majors is aimed at investigating structure-function relationships in the bacterial F1F0 ATP synthase. This research makes very heavy use of modern molecular biology techniques, bacterial genetics and enzymology. Most experiments involve site-directed mutagenesis and biochemical methods. The second project investigates the regulation of the mammalian renal H,K-ATPase. Work in this area is most suitable for a student interested in molecular biology and gene regulation. Ongoing research makes use of mammalian tissue culture, reporter gene technology, microarrays and a wide variety of recombinant DNA and blotting methods.
Requirements: We prefer students in their sophomore or junior years. Students majoring in IDS-Biochemistry, Microbiology and Chemistry are the most appropriate people.
Starting Date: Sept 2002
Ending Date: open
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Edward Chan
Field of Research: Autoimmunity/Cell Biology
Phone Number:
E-mail: echan@ufl.edu
Project Description: Our laboratory is primarily interested in autoimmunity with the focus in autoantigens involved in systemic autoimmune diseases and cancer. We are interested in the molecular and cell biology of important macromolecules and subcellular organelles which have become autoimmune targets. Students may learn molecular biology how to express recombinant proteins using a bacterial and other expression systems, produce milligram amount of antigens, and develop immunological assays such as ELISA, Western blotting, etc. Other methods include combination of recombinant DNA, tissue culture, and immunofluroescence microscopy.
Requirements: Please provide current college transcript. Background that includes laboratory coursework in molecular biology, microbiology, cell biology, and/or immunology preferred.
Starting Date: Flexible
Ending Date: Flexible
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Thomas Crisman
Field of Research: Ecology
Phone Number: 352-846-2150
E-mail: marcgris@ufl.edu
Project Description: Our study focuses on the effects of forest management strategies on stream communities. Specifically we are examining changes in habitat patch type on invertebrate communities. Students on this project will be involved in both laboratory and field work. Laboratory work will involve sample processing and identification on aquatic macroinvertebrates. Further work may involve experiments on movement patterns of invertebrates and digital image analysis. Field work will include macroinvertebrate, periphyton and leaf litter sampling.
Requirements: Interest in aquatic ecology with preference for students experienced in invertebrate identification.
Starting Date: 3/26/2005
Ending Date: 4/20/2007
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: James Cuda
Field of Research: Weed Biological Control
Phone Number: 352-392-1901 x 126
E-mail: jcuda@ufl.edu
Project Description: 1. Classical Biological Control of the Invasive Weed Brazilian peppertree (Schinus terebinthifolius)in Florida. 2. Classical Biological Control of the Aquatic Weeds Hydrilla (Hydrilla verticillata) and Hygrophila (Hygrophila polysperma) in Florida.
Requirements: Courses and laboratory experience working with arthropods (insects and mites) and/or plants Flexible work schedule; willing to work on weekends
Starting Date: 1 October 2006
Ending Date: 30 September 2007
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Not Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Jesse Dallery
Field of Research: Behavioral Pharmacology
Phone Number: 392-0601 ext 276
E-mail: dallery@ufl.edu
Project Description: Laboratory and applied research on nicotine and smoking. Laboratory research on the effects of nicotine (and other drugs of abuse) on choice. Applied research on behavioral treatments for cigarette smoking.
Requirements: Interest in behavior.
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: John Dame
Field of Research: Molecular Microbiology
Phone Number: 392-4700 x 5818
E-mail: damej@mail.vetmed.ufl.edu
Project Description: The human malaria parasite, Plasmodium falciparum, is an intracellular parasite that infects 500 million people each year in tropical and subtropical areas of the world. No vaccine is available and antimalarial drugs are losing efficacy. We culture the asexual phase of the life cycle continuously in human red cells in vitro. Recently the genome of this parasite has been completely sequenced and new tools for genetic manipulation have been developed. We are using these genetic tools to identify, among the gene products predicted from the genome sequence, potential antimalarial drug targets. Currently, we are looking for assistance in our research on the DNA gyrase encoded in the genome.
Requirements: Upperlevel coursework in microbiology, molecular biology,and biochemistry. Sufficient time available each week to contribute reliablly to ongoing projects. Laboratory experience and demonstrated interest or experience in tropical diseases, parasitology, or continuous cell culture desired.
Starting Date: Immediately
Ending Date: Ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Jaret Daniels
Field of Research: Entomology/Conservation
Phone Number: 392-1901 ext. 121
E-mail: jcdnls@ufl.edu
Project Description: Conservation of the endangered Miami blue butterfly-one of the nation's rarest insects. The project involves various related laboratory and field research opportunities that focus on captive breeding and maintenance, organism reintroduction, molecular diversity and inbreeding depression, population biology, and ant-larval interactions. Research can be completed at UF as well as in a number of south Florida field locations and will involve direct interation with graduate students.
Requirements: Interest and background in biology. May involve occasional travel-depending on research project. Fexible hours.
Starting Date: 9/1/06
Ending Date: NA
Academic Year Positions: Not limited
Summer Positions: Not limited
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Jaret Daniels
Field of Research: Biology/Entomology
Phone Number: 392-1901 ext. 121
E-mail: jcdnls@ufl.edu
Project Description: The Florida Butterfly Monitoring Network (FBMN) is a statewide citizen scientist program that trains public volunteers and directly engages university scientists, zoological institution staff members, and conservation land managers in field-based conservation and education targeting butterflies. FBMN participants provide up-to-date information on Florida's diverse butterfly fauna. The data collected will be used to assess the distribution and population trends of both common and imperiled species. This information will facilitate the development of appropriate species’ conservation and management strategies. Students will help monitor butterflies on a number of conservation land areas in Alachua county and adjacent counties. Additional opportunities for education material development are available.
Requirements: Interest in biology a plus. Willingness to work in the field. Must have own transportation.
Starting Date: Anytime
Ending Date: No end date
Academic Year Positions: Not limited
Summer Positions: Not limited
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Ben Dunn
Field of Research: Protein Engineering
Phone Number: 352 392-3362
E-mail: bdunn@college.med.ufl.edu
Project Description: Multiple projects dealing with relation of structure/function of proteolytic enzymes (PRs). Use of molecular biology for site-specific mutogenesis, protein expression, enzyme kinetics. Projects: a) HIV PR b) Malaria PRs c) Human Cathepsins d) FIV PR e) protein inhibitors f) Chimeric Proteins and protein folding g) tuberculosis protease h) Serine PRs of bacteria and fungi. Preference given to students in their second year at UF.
Requirements: Organic Chemistry, Biology, Interest in Biochemistry
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3-5
Summer Positions: 3-5
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Rodney Edwards
Field of Research: Obstetrics/Infectious Diseases
Phone Number: 392-3306
E-mail: edwardsr@obgyn.ufl.edu
Project Description: Our research program is focused on infections in pregnancy, preterm delivery, and the interaction between these two topics. Currently, the work in our laboratory is centered around the study of genes and gene products responsible for the inflammatory response that is mounted against pathogens and is responsible for many preterm deliveries. In addition to basic science-type projects, our group also is engaged in clinical research.
Requirements: For laboratory-based projects, classes in basic microbiology, molecular biology, and laboratory instruction in sterile technique are a must. For clinical research projects, one must be able to work independently and have some experience with computer data entry. For either type of project, the student should be responsible, highly motivated, and able to maintain a flexible schedule.
Starting Date: variable
Ending Date: variable
Academic Year Positions:
Summer Positions:
Independent Study: Not Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Captive propagation and reintroduction of the endangered Miami Blue butterfly.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Captive propagation and reintroduction of the endangered Miami Blue butterfly.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Chromosome evolution in butterflies and moths.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Behavior of tropical butterflies in the Butterfly Rainforest facility (nocturnal social roosting aggregations; territoriality; courtship and mating; nectaring and fruit-feeding; sound production; etc.).
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Museum techniques with Lepidoptera (training in specimen preparation, curation, taxonomy and classification).
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Florida native wildflowers and butterfly gardening.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Greenhouse and shadehouse culture of larval host plants and adult nectar plants.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: David Evans
Field of Research: Comparative Physiology
Phone Number: 392-1489
E-mail: devans@zoo.ufl.edu
Project Description: We are interested in various aspects of fish physiology, usually focused on the role of the gill in salt and water regulation in marine fishes. In the next few years we will be investigating our hypothesis that local signaling agents, such as nitric oxide, endothelin, and prostaglandins, play a role in controlling gill perfusion and active transport of salts across the gill epithelium. For more information, visit my web site: www.zoo.ufl.edu/dhefish.
Requirements: One year of biology and chemistry, but organic chemistry and upper division status are preferred.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Ira Fischler
Field of Research: Cognitive Psychology
Phone Number: 392-0601 x 228
E-mail: ifisch@ufl.edu
Project Description: As one of several projects under UF's NIMH-sponsored Center for the Study of Emotion and Attention, we conduct research on the comprehension of emotional aspects of words and sentences, as measured by the electroencephalographic (EEG) activity that is recorded during various tasks. We've found that emotiona words produce distinct patterns of EEG activity compared to nonemotional words, but that these patterns are influenced by the attentional focus during the tasks. Undergraduates have parti- cipated extensively in these studies, and two seniors are currently doing IDS research projects under my direction.
Requirements: At least the general psychology course (PSY 2013) and one more advanced course in either cognitive or sensory psychology, psychobiology, or biology.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Bradley Fletcher
Field of Research: Molecular Biology
Phone Number: 392-8558
E-mail: bsf@college.med.ufl.edu
Project Description: Our laboratory is interested in using transposons as delivery vehicles for therapeutic gene therapy. We have made significant modifications to the Sleeping Beauty transposon in order to increase its efficiency. We utilize cationic lipids or other polymers to deliver plasmid DNA to rodent models. Our emphasis is on targeting delivery to endothelial cells to treat specific conditions including hemophilia, hypertension and cancer. Additional interests in the laboratory include retroviral expression cloning.
Requirements: Basic knowledge of molecular biology and genetics. Strong commitment to, and adequate time for, research (minimum two or more semesters). Upper classmen (junior/senior) preferred, but exceptions can be made. Students majoring in IDS-Biochemistry and Microbiology and are the most appropriate people.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Bradley Fletcher
Field of Research: Molecular Biology
Phone Number: 392-8558
E-mail: bsf@pharmacology.ufl.edu
Project Description: Our laboratory is interested in using TRANSPOSONS as delivery vehicles for therapeutic GENE THERAPY. We have made significant modifications to the Sleeping Beauty transposon in order to increase its efficiency and we are testing a new transposon system called piggyBac. We utilize cationic lipids or other polymers to deliver plasmid DNA to rodent models. Our emphasis is on targeting delivery to endothelial cells to treat specific conditions including hemophilia, hypertension and cancer. Additional interests in the laboratory include retroviral expression cloning.
Requirements: Basic knowledge of molecular biology and genetics. Strong commitment to, and adequate time for, research (minimum two or more semesters). Lower classmen preferred(sophmore/junior)so adequate time can be deicated toward resech, but exceptions can be made. Students majoring in IDS-Biochemistry and Microbiology and are the most appropriate people.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 4
Summer Positions: 4
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Kevin Folta
Field of Research: Plant Molecular Bio, Physiology
Phone Number: 846-2339
E-mail: kfolta@ifas.ufl.edu
Project Description: We have two reserach tracks: 1. SIGNAL TRANSDUCTION-- My laboratory is interested in control gene expression and developmental events surrounding the transition between plant growth in darkness and growth in light. This process, photomorphogenesis, involves the coordinated activities of a number of photoreceptors and signal transduction pathways. We are using a multi-faceted approach, incorporating physiological, genomic, biochemical and genetic methods to dissect light signaling networks. Expect to learn valuable basic techniques in gene discovery, plant physiology and DNA/RNA manipulation. ***Just about all undergraduate researchers that have shown commitment to the work have found publication in peer-reviewed journals.***
Requirements: Commitment to the project is essential. We will design a project that will mesh well with your specific backgrounds and interests. Any lab experience will prove valuable, but we will train you. Preference given to students with plant science interests, especially those considering graduate training in plant biology.
Starting Date: any time
Ending Date: none
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Kevin Folta
Field of Research: Plant Genomics, Molecular Biology
Phone Number: 846-2339
E-mail: kfolta@ifas.ufl.edu
Project Description: STRAWBERRY GENOMICS - We have an ambitious program to study structural, functional and translational genomics in this important Florida crop. Our research stategy uses molecular tools to understand the basis of processes important to agriculture. We have outstanding tools to perform groundbreaking work and seek abmitious students to aid in these pursuits. Expect to learn valuable basic techniques in gene discovery, plant physiology and DNA/RNA manipulation. ***Just about all undergraduate researchers that have shown commitment to the work have found publication in peer-reviewed journals.***
Requirements: Commitment to the project is essential. We will design a project that will mesh well with your specific background and interests. Any lab experience will prove valuable, but we will train you. Preference given to students with plant science interests, especially those considering graduate training in plant biology.
Starting Date: any time
Ending Date: none
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Richard Frye
Field of Research: Neurological Basis of Learning Disabilities
Phone Number: 352-273-5778
E-mail: fryerich@peds.ufl.edu
Project Description: Learning Disabilities may affect as many as 10-15% of children. Although, educationally -based remediation can help individuals improve their skills, recent research has demonstrated that residual cognitive difficulties extend into adulthood. Despite the advances in our knowledge about the brain and behavior, the neurological basis of many Learning Disabilities is still largely unknown and controversial. The Division of Pediatric Neurology has coordinated the flagship state funded Learning Disabilities Clinic for over 20 years. This clinic is fueled by the collaboration of a multidisciplinary team that includes Education, Psychology and Neuropsychology specialists. Over the past several years we have built a research database that contains the results of our comprehensive evaluation of children with various learning problems. We also have ongoing neuroimaging experiments using magnetoencephalography (MEG) and functional MRI. We seek students with several projects including: (1) statistical modeling of data derived from our database, (2) analysis of MEG data, and (3) assisting with neuroimaging in the pediatric population.
Requirements: Depending on project, candidate may require (1) knowledge in experimental design and statistics, (2) excellent interpersonal skills and an ability to work with children, and/or (3) knowledge of neuroimaging methods.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions:
Summer Positions: 2
Independent Study: Not Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Maria Gallo-Meagher
Field of Research: Molecular biology and tissue culture
Phone Number: 392-1823
E-mail: mgmea@ifas.ufl.edu
Project Description: To aid in investigations for the development of genetic transformation systems in peanut.
Requirements: biology major with lab experience
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Dovie Gamble
Field of Research: All Disciplines
Phone Number: 846-2575
E-mail: dgamble@ufl.edu
Project Description: The McNair Program is designed to provide undergraduates with effective preparation to enter and complete doctoral programs. Students perform research with a faculty mentor and attend seminars and workshops on topics relevant to doctoral study. Please note that the salary noted below is actually in the form of a Research Stipend.
Requirements: Low income, first generation college student and/or underrepresented minority; U.S. citizen or permanent resident; 3.0 or higher GPA
Starting Date: Fall (each year)
Ending Date: Summer A
Academic Year Positions: 30 funded
Summer Positions: Summer A only
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Not Available

Principal Investigator: Daniel Hahn
Field of Research: Diabetes and Obesity, in Insects
Phone Number: 392-1901x156
E-mail: dahahn@ifas.ufl.edu
Project Description: Our lab uses insects as models for basic physiological processes in human diseases. One current project explores how flies regulate blood sugar and fat loads in response to seasonal cycles. Flies enter a hibernation-like state during the winter; and like hibernating grizzly bears, over wintering flies accumulate greater fat stores than summer flies. We are studying the roles of two important endocrine signaling pathways in this process, insulin (yes, flies have an insulin signaling system!) and the glucagon-like adipokinetic hormone in this process.
Requirements: Student must be willing to work hard and learn new things. No experience necessary, but prior coursework in biology and chemistry a plus.
Starting Date: various
Ending Date: various
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Daniel Hahn
Field of Research: Ecology, Evolution, & Physiology
Phone Number: 392-1901x156
E-mail: dahahn@ifas.ufl.edu
Project Description: How important is size? Our lab combines techniques from a number of fields including ecology, evolutionary biology, physiology and biochemistry to determine how traits such as body size and nutritional status affect survival and reproduction in insects. Training could include a number of techniques including behavior, field collections, artificial selection, respirometry, molecular genetics/proteomics and analytical biochemistry.
Requirements: Student must be willing to work hard and learn new things. No experience necessary, but prior coursework in biology and chemistry a plus.
Starting Date: various
Ending Date: various
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: william haller
Field of Research: invasive plant management/biology/control
Phone Number: 352-392-9615
E-mail: wth@ifas.ufl.edu
Project Description: Fellow faculty and I are involved in many aspects of invasive aquatic, wetland and upland plant biology, control and ecological effects of control efforts,, fire, mechanical, chemical and biological. We are located at the Center for aquatic and invasive plants, 9 miles northwest of campus off millhopper road, so transportation will be a necessity. See our website at http:/plants.ifas.ufl.edu for more details. Research is currently (2006) bein conducted on old world climbing fern, air potato, ardisia, hydrilla, water lettuce and water hyacinth,, and even a survey of invasive duckweeds in florida.., we are even evaluating the food consumption,, ie. aquatic plant consumption of native versus exotic apple snails. Specific research includes growth and reproduction, productivity, effects of invasive plants on aquatic ecosystems and aquatic and other invasive weed control programs..The Center for Aquatic and Invasive Plants also cooperates with the World Bank in Washington, DC to place a UF undergraduate student interested in invasive species into a summer internship at the WB in DC. Socicitations for this competitive internship will be sent out in early January. Contact haller for further details.
Requirements: A willingness to work the task to the end,, and interest and enthusiasm for research and finding answers.....its not easy work and you sweat once in a while!!!
Starting Date: Anytime
Ending Date: flexible
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Nancy Hardt
Field of Research: Pathology
Phone Number: 395-0238
E-mail: hardt@pathology.ufl.edu
Project Description: Maintain extensive database of breast implant cases. Database can be used to develop avenues of inquiry according to the student's interest. Histology experience would be helpful.
Requirements: Must be capable of independent work. Histology helpful. I will teach any pathology needed. Must be facile with spreadsheet Programs. The database is currently in Quattro.
Starting Date: 1/1/97
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Brian Harfe
Field of Research: Developmental Biology/Genetics
Phone Number: 352-392-1642
E-mail: bharfe@mgm.ufl.edu
Project Description: The goal of this project is to understand the molecular pathways responsible for joint formation during development. Joints form from the condensation of mesenchymal cells. Members of the TGF? superfamily have been shown to play an important role in specifying joint formation. In particular, members of the TGF? Bmp5/6/7 andGdf5/6/7 subfamilies are known to be important for joint formation. However, the role of the Bmp-2/4 subfamily has not been analyzed during joint formation since Bmp-2 and Bmp-4 null mouse embryos die before the joints form. We have created limb-specific knockouts of Bmp-2 and Bmp-4 in mice to analyze joint formation when these proteins are absent. We are also crossing these tissue-specific knockouts to additional mouse mutants known to have joint defects. This information will aid in the development of treatments for the large number of joint problems present in the human population. This project involves extensive work with mice in the SPF facility and common molecular biology techniques. Students who can commit to working in the lab for at least 12 hours a week for a year or longer are encouraged to apply. Upon completion of this project, the student will be well positioned for further research in the fields of developmental biology and genetics.
Requirements: Students should have completed basic biology classes. A working knowledge of molecular biology and genetics would be very useful. Students are expected to be in the lab at least 12 hours a week for an entire academic year. This project involves an extensive use of mice including harvesting embryos.
Starting Date: Late Spring 2004 or Summer 2004
Ending Date: Variable
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Alice Harmon
Field of Research: plant biochemistry
Phone Number: 352 273-8096
E-mail: harmon@.ufl.edu
Project Description: The goal of this project is to biochemically characterize representative members of the CDPK family. CDPKs (calcium-dependent protein kinases) are involved in sensing intracellular calcium signals and bringing about cellular responses to external stimuli. In the model plant Arabidopsis, there are 34 genes that encode CDPKs. The student will be involved in cloning cDNAs encoding CDPKs into a bacterial expression vector and expressing CDPK proteins and purifying them. The student will assist in characterization, including crossreactivity to antibodies, analysis of autophosphorylation sites by mass spectrometry, and substrate specificity tests.
Requirements: Requirements: A strong background in chemistry is required. Students who have taken or are taking biochemistry will be given preference. Students should be able to work 10-15 hours per week during Spring Semester and 20-30 hours per week in the summer of 2007. Applications from underrepresented minorities and women are encouraged.
Starting Date: January, 2007
Ending Date: August 2007
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Not Available

Principal Investigator: Mirian Hay-Roe
Field of Research: Ecology, lepidoptera biology
Phone Number: (352)846-2000 Ext 478
E-mail: mmhr@ufl.edu
Project Description: Chemical interactions between butterflies of the genus Heliconius and their hostplants Passiflora, and the implications of such interactions on the organization of natural communities and the evolution of species.
Requirements: Background in Biology, responsible, dynamic. Morning availability.
Starting Date: 09/01/06
Ending Date: N/A
Academic Year Positions: Not limited
Summer Positions: Not limited
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Jacqueline Hobbs
Field of Research: Psychiatry, Virology
Phone Number: 352-294-0412
E-mail: jahobbs@psychiatry.ufl.edu
Project Description: My laboratory is interested in the basic biology of parvovirus-brain interactions. Parvoviruses are small DNA-containing viruses. There are two parvoviruses of human concern: 1) adeno-associated virus (AAV) which is not known to cause human disease, and 2) parvovirus B19 (B19) which causes multiple human disorders from benign to life-threatening conditions. There is some clinical evidence that B19 can infect the brain and cause disease, but very little is known about this area. We are asking the questions of whether or not these viruses infect the brain and at what point in neural development is the infection most likely to occur. We are also determining what factors enhance the ability of these viruses to infect brain cells. Another area of interest in the lab is potential viral etiologies of mental illnesses such as schizophrenia, bipolar disorder, and autism. We have a large number of post-mortem human brain tissues for studies. Our studies utilize the following techniques: cell culture, polymerase chain reaction (PCR), RT-PCR, nested PCR, flow cytometry, and RNA/DNA analysis by agarose gel electrophoresis. There are a variety of projects that could be undertaken by undergraduate students.
Requirements: This position requires that the applicant pay attention to small details, be very organized and neat.
Starting Date: ongoing
Ending Date: ongoing
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Sidney Homan
Field of Research: English, Theatre
Phone Number: 352-378-9166
E-mail: shakes@ufl.edu
Project Description: I recently lost one of my two Honors research assistants because of illness and am here seeking to replace him. I am finishing a book called CHALLENGES INTHE THEATRE (about productoins that make unusual demands on directors, actors, and audience, demands beyond the normal) and need a research assistant to: 1. help prepare an anntated bibliogrpahy of recent scholarship on and productions of the several plays treted in tthe book (from Pinter's NO MAN'S LAND to Shakespeare's AS YOU LIKE IT, among others); 2. serve as a collborator, a consultant on the manuscript (translation: your opinion of the book counts!); 3. and help proof the manuscript.
Requirements: 1. facility using the internet; 2. and the library; 3. someone who enjoys the theatre and playing the role of editor
Starting Date: as soon as possible
Ending Date: could extent through spring semester
Academic Year Positions: one or two
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Jeffrey Hughes
Field of Research: Gene Therapy
Phone Number: 352-846-2725
E-mail: hughes@cop.health.ufl.edu
Project Description: My lab studies the underlying principles of macromolecule movement. We then use these finding to design better drug delivery systems. In particular, recently we have been interested in using cationic lipids to transport nucleic acids into cells in the aim of treating diseaes. In addition, we are also very interested in factors which can influence cell membranes and consequences on biological activity.
Requirements: Basic Chemsitry and Biology Courses
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Margaret James
Field of Research: Drug Metabolism
Phone Number: 352 846 1952
E-mail: mojames@ufl.edu
Project Description: Study of the effect of celecoxib on the sulfotransferase enzyme. Research in this laboratory has shown that celecoxib, an analgesic and cyclo-oxygenase 2 inhibitor, influences the biotransformation of several drugs and steroids. The project will further examine the interaction of celecoxib with drug-metabolizing enzymes.
Requirements: Chemistry or biochemistry major
Starting Date: flexible
Ending Date: flexible
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Sally Johnson
Field of Research: Cell Biology/Muscle repair
Phone Number:
E-mail: sjohnson@animal.ufl.edu
Project Description: Adult muscle stem cells, also referred to as satellite cells, reside within normal tissue in a mitotically inactive state. Upon injury or growth stimuli, the cells exit quiescence, proliferate and subsequently differentiate into the large muscle fibers responsible for contractile motion. Hepatocyte growth factor and Notch signaling pathways are crucial to the activation of myogenic stem cells. However, the events and signals necessary for return of a daughter cell to the dormant state remains largely unknown. Thus, the goal of this project is identify marker proteins that participate in cell cycle arrest in satellite cells.
Requirements: The student should have completed coursework in biology, biochemistry or molecular biology. A general working knowledge of laboratory procedure is preferred.
Starting Date: 2/1/2006
Ending Date: TBA
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: David Julian
Field of Research: Ecological physiology
Phone Number: 392-5878
E-mail: julian@zoo.ufl.edu
Project Description: The focus of my laboratory is on ecological and comparative physiology. We are currently investigating the cellular and molecular adaptations of marine and aquatic invertebrates to hypoxia, environmental toxins and other physiological stresses. The objectives of our research are twofold: first, we hope to understand how some marine invertebrates can tolerate, and even thrive, in extreme and seemingly toxic conditions, and second, we hope to clarify the cellular and molecular mechanisms by which humans and other vertebrates are affected by these same challenges. In this research, we use a variety of animal and in vitro models, including marine worms, aquatic fish, the nematode C. elegans, and mammalian neuronal and glial cell cultures. Students in my lab can learn a variety of techniques, including cell culture, molecular biology, electrophysiology, histology, electron microscopy, enzyme biochemistry and respirometry. More information is available at the lab's web site: http://www.zoology.ufl.edu/julian/
Requirements: One year each of biology and chemistry. Upper division status helpful, but not required.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: David Julian
Field of Research: Comparative and Ecological Physiology
Phone Number: 392-5878
E-mail: julian@zoo.ufl.edu
Project Description: The focus of my laboratory is on ecological and comparative physiology. We are currently investigating the cellular and molecular adaptations of marine and aquatic invertebrates to hypoxia, environmental toxins and other physiological stresses. The objectives of our research are twofold: first, we hope to understand how some marine invertebrates can tolerate, and even thrive, in extreme and seemingly toxic conditions, and second, we hope to clarify the cellular and molecular mechanisms by which humans and other vertebrates are affected by these same challenges. In this research, we use a variety of animal and in vitro models, including marine worms, aquatic fish, the nematode C. elegans, and mammalian cell cultures. Students in my lab can learn a variety of techniques, including cell culture, molecular biology, electrophysiology, histology, electron microscopy, enzyme biochemistry and respirometry. More information is available at the lab's web site: http://www.zoo.ufl.edu/julian/
Requirements: One year each of college biology and chemistry (all with an A grade). Prior research experience is not required. Sophomore or junior status preferred, but not essential.
Starting Date: Ongoing
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Michael Katovich
Field of Research: physiology
Phone Number: 392-3292
E-mail: katovich@cop.ufl.edu
Project Description: Investigate various models of experimental hypertensive rat models. Major emphasis is alterations in the renin angiotensin system and its influence on the development of hypertension and related cardiovascular complications. In vivo and in vitro measurements are made. Cell culture experiments to complement the animal experiments are also performed in the lab.
Requirements: anyone in the lab will have to undergo training through IACUC (on line) to be approved to use animals. individual should not have any allergies to rodents.
Starting Date: variable
Ending Date: variable
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Maureen Keller-Wood
Field of Research: Physiology and Pharmacology
Phone Number:
E-mail: kellerwd@cop.ufl.edu
Project Description: During pregnancy maternal physiology is altered. One of these adaptations is change in secretion of steroid hormones by the adrenal gland. Our studies suggest that these changes are crucial for both maternal health and fetal well-being. Current research interests in the lab include the effects of steroid hormones from the adrenal and placenta on the maternal brain and vasculature during pregnancy, and effects of maternal adrenal steroid secretion on fetal physiology, including effects on fetal lung, kidney, brain and heart. Potential projects would incorporate methods such as real-time PCR measurement of mRNA for target genes induced by steroid action, and Western blot and immunohistochemical analysis of the corresponding proteins.
Requirements: undergraduate level biology and chemistry including some laboratory coursework
Starting Date: Fall 2006
Ending Date:
Academic Year Positions: 2
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Soo-Jeong Kim
Field of Research: Genetics of Neurodevelopmental Disorders
Phone Number: 352-392-7322
E-mail: soojkim@ufl.edu
Project Description: We are interested in finding contributing genetic factors for specific behavioral and psychiatric phenotypes of neurodevelopmental genetic disorders. Currently, we have enlisted two clinical populations for our study: Autism Spectrum Disorder and Prader-Willi syndrome. Our project consists of clinical assessments of participating subjects (phenotypic assessment) and molecular genetic study (genotyping) to find phenotype-genotype correlations.
Requirements: Applicants interested in clinical assessments are required to have good clinical manner and motivation to learn new diagnostic assessments. Applicants interested in molecular genetic study are required to have motivation to learn new molecular genetic study protocols, such as DNA extraction, quantification, and genotyping. Strong work ethics and motivation are most important.
Starting Date: ASAP
Ending Date: NA
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Prof. F. Wayne King
Field of Research: Herpetology
Phone Number: 352 392 6573
E-mail: kaiman@flmnh.ufl.edu
Project Description: The Florida Museum of Natural History, Division of Herpetology, maintains major webpages on 'Herpetology', 'Herpetology Programs at the UF' (including courses offered in WEC, ZOO, GEO, and VME), 'Herp Faculty, Grad Students, and Alumni', 'Fieldguides to Florida Reptiles and Amphibians', 'Crocodilians', 'Crocodilians, Tuatara, and Turtle Species of the World' and other topics related to amphibians and reptiles (including thousands of pages and hundreds of images). The public accesses these pages thousands of times each day for information about reptiles and amphibians. Assistance is needed in formatting these pages and images for the web, keeping them current, checking broken links, and developing other exciting pages of interest to professional and amateur herpetologists, reptile and amphibian pet keepers, students, and the general public.
Requirements: Knowledge of webpage formatting, including html, dhtml, and/or xml; use of web page development/editing software and photo/image processing software. Though not required, a strong background in graphic arts would be an asset.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: contact faculty mentor
Summer Positions: contact faculty mentor
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Harry Klee
Field of Research: Molecular Biology
Phone Number: 392-8249
E-mail: hjklee@ifas.ufl.edu
Project Description: Our lab is working to understand the molecular mechanisms whereby the hormone ethylene acts to control plant growth and development. Ongoing projects available for independent study include gene identification, protein-protein interactions and production of transgenic plants. These projects offer opportunities to learn basic molecular biology, biochemistry and tissue culture skills. The projects are aimed at identifying the gene products involved in hormone signal transduction.
Requirements: Molecular biology and microbiology courses would be very helpful, particularly lab courses. Commitemt to and enthusiasm for science are essential.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Christiaan Leeuwenburgh
Field of Research: Biochemistry of Aging
Phone Number: 352-392-9575 (1356)
E-mail: cleeuwen@ufl.edu
Project Description: Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. In both humans and animals, the aging process in several irreplaceable post-mitotic tissues (e.g., heart, skeletal muscle, and brain) has been associated with a decrease in the total number of cells. So a reduction in the total number of viable cells may lead to an accelerated decline in function in the heart, skeletal muscle, and brain. In addition to cell loss via apoptosis may be a major factor contributing to the loss of post-mitotic cells with age. The term apoptosis is used to describe programmed cell death, a type of cell death involved in cellular development distinct from necrosis. Generally, apoptotic cells die by design whereas necrotic cells die due to accident and lethal injury. Senescent aging likely involves both programmed changes in gene expression and 'wear and tear' mechanisms, such as oxygen radicals, mitochondrial DNA damage, and the formation of glycooxidation products also called advanced glycation end products (AGE). Programmed changes in gene expression and 'wear and tear' mechanisms are likely interlinked, and both may contribute to apoptosis. Although evidence exists that the incidence of apoptosis increases in post-mitotic cells with age, there are few studies to date that have attempted to identify the molecular mechanisms underlying the cell loss. Recent evidence suggests that mitochondria may play a key role in regulating apoptosis. With aging, the radical production by mitochondria can lead to increased oxidative stress. Oxidative stress is one of the many death-inducing signals, which can trigger mitochondria to release caspase-activating proteins such as cytochrome c and apoptosis inducing factor. In our studies, we examined the role that mitochondria play in influencing apoptosis in the heart, brain, and skeletal muscle. If the mechanisms underlying the cell loss with age can be identified, it could help explain the loss of function with age and may lead to specific therapeutic interventions that could attenuate this cell loss.
Requirements: Biochemistry and Interest in Aging Research
Starting Date: Summer 2002
Ending Date: Fall 2003
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Christiaan Leeuwenburgh
Field of Research: Biochemistry of Aging
Phone Number: 352-392-9575 (1356)
E-mail: cleeuwen@ufl.edu
Project Description: Senescent aging probably involves both programmed changes in gene expression, “wear and tear” mechanisms such as oxidative stress by oxygen radicals, mitochondrial DNA damage, the formation of glycooxidation products, and failure of repair mechanisms. Moreover, recent work suggests that mitochondria may play a key role in regulating apoptosis due to chronic life-long radical production by mitochondria leading to an increase in oxidative stress associated with mitochondrial DNA deletions, DNA damage and apoptosis. Although evidence exists that the incidence of apoptosis increases in post-mitotic cells with age, there are few studies to date that have attempted to identify the molecular mechanisms underlying this cell loss.
Requirements: Keen interest in Biochemistry and Cell Biology
Starting Date: 2004
Ending Date: 2006
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Ann Marie LeVine
Field of Research: Lung
Phone Number: 3523921189
E-mail: levineam@peds.ufl.edu
Project Description: The laboratory focuses on lung injury and repair with emphasis on the surfactant proteins and their role in host defense. The immune response of the lung to bacterial and viral infection is also under investigation.
Requirements: Enthusiastic, energetic and willing to learn There is sufficient personel in the laboratory to train and teach new molecular biology techniques
Starting Date:
Ending Date:
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Daiqing Liao
Field of Research: Cancer Biology, Molecular Cell Biology, Virology
Phone Number: 352-294-7976
E-mail: dliao@ufl.edu
Project Description: Our research program focuses on understanding function and regulation of tumor suppressor p53 and its homologous transcriptional activators by viral oncogenes and cellular proteins. In one project, we are studying how adenovirus E1B 55-kDa oncoprotein impacts on p53 pathway and roles of this viral oncoprotein in cell transformation induced by adenovirus, a DNA tumor virus. We have found that the E1B 55-kDa protein inhibits p53’s functions through several distinct biochemical mechanisms including inhibition of posttranslational modifications of p53, sequestration of p53 in the cytoplasm and impairs regulation of p53 by cellular proteins. Current efforts focus on understanding how E1B 55-kDa oncoprotein represses transcription and potential role of cytoplasmic sequestration of p53 by this viral oncogene in apoptosis. In another project, we are investigating the interplay between acetylase and coactivator PCAF and p53 family of proteins and the impact of their interactions on expression of p53 target genes and on tumor suppression. We are also interested in understanding how stresses relay signals to p53. To this end, we have found that p53 is phosphorylated at specific serine residues in the C-terminal regulatory domain by a yet to be identified kinase. We are making progress in identify this kinase through proteomic approaches. Our goal here is to identify this kinase and study its role in signaling pathways converging on p53. Finally, we have been interested in understanding the interactions between p53 family proteins and Daxx. We and others have found that Daxx binds to p53 and p73. These interactions may play important roles in the diverse functions of Daxx ranging from transcriptional regulation to apoptosis, as well as cell cycle control. Our long-term goal is to understand the cellular regulatory circuitries that govern cell growth and transformation through focused research on the p53 pathway by using cutting-edge technologies in cell biology, genomics and proteomics. We believe that such approaches will likely yield useful knowledge that will have major impact in cancer cell biology and may also have translational values in designing treatments for cancer patients. See: http://plaza.ufl.edu/dliao/
Requirements:
Starting Date: Open
Ending Date: Felxible
Academic Year Positions:
Summer Positions: Two
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Sally Litherland
Field of Research: Immunology
Phone Number: 352 392-5169
E-mail: litherla@pathology.ufl.edu
Project Description: Analysis of Signal transduction dysregulation in autoimmune diseases.
Requirements: Interest in medically applicable research; chemistry & biological sciences coursework, hepatitis B & tetanus vaccinations.
Starting Date: open
Ending Date: open
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Bin Liu
Field of Research: Neurodegenerative diseases
Phone Number: 352 392-3972
E-mail: bliu12@ufl.edu
Project Description: Neurodegenerative diseases such as Parkinson's and Alzheimer's disease remain a major challenge in our search for a causative factor and cure. With an increasingly aging population, it is ever more urgent to gain a better understanding of the disease process. The focus of this laboratory is two-fold. First, we investigate the effect of exposure to environmental toxins on the development of Parkinson’s disease. Second, deciphering the mechanism responsible for the neurodegenerative process offers us unique targets for designing novel therapeutic approaches for the treatment of the disease. Neural cell culture and rodent models are used in our studies. Techniques routinely used in the laboratory include cell culture, establishment of primary cultures, enzyme activity, protein analysis, Western blot, immunostaining, neuronal function assays, cytokine analysis, and free radical determination.
Requirements: Basic chemistry and biology
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Chen Liu
Field of Research: Immunology, Vriology, and Genetics
Phone Number: 352-273-5413
E-mail: liu@pathology.ufl.edu
Project Description: There three research areas in my laboratory: 1. Immunology and Virology of Hepatitis C Virus. We are interested in the mechanisms of viral replication, antiviral agents, innate and adaptive immunity, and vaccine development; 2. Oncogenes and Cancer. We are interested in oncogene mutation analysis of patient cancer tissues; 3. Alpha-1 antitrypsin deficiency and Liver disease. We are interested in finding therapeutic molecules to treat this genetic disease.
Requirements: Biology or science-related major.
Starting Date: Flexible
Ending Date: flexible
Academic Year Positions: flexible
Summer Positions: flexible
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Joanna Long
Field of Research: Biochemistry & Molecular Biology
Phone Number: x6-1506
E-mail: jrlong@mbi.ufl.edu
Project Description: Multiple projects examining protein structure and function in lipid membranes and extracellular matrices. Use of molecular biology or solid phase peptide synthesis for protein expression, biophysical characterization techniques, spectroscopy, computer modeling. Projects: 1) Ion channel function in heterogeneous membranes, 2) Mechanism of lung surfactant protein B, 3) Bone Sialoprotein and biomineralization, 4) Integrin association in membranes. Preference given to students in their second year at UF.
Requirements: Basic knowledge of biology, chemistry and molecular; undergraduate organic chemistry or microbiology lab preferred.
Starting Date: open
Ending Date: open
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas H. Mareci, Ph.D.
Field of Research: Biophysics and Biochemistry
Phone Number: 392-3375 or 392-2332
E-mail: thmareci@ufl.edu
Project Description: Our research focuses on the study of fundamental questions of tissue structure and biochemical processes in living systems accessible to study with nuclear magnetic resonance (NMR) techniques. To provide a detailed understanding of the living system, we are examining excised tissue with MR microscopy and spectroscopies then these measurements are extended to studies in vivo. This work involves a detailed investigation of biophysical processes at the cellular and molecular level along with the development of NMR measurement and processing methods, and specialized hardware. Our current projects are the following: 1) We are studying blood-spinal-cord barrier and blood-brain-barrier disruption, using dynamic contrast enhanced MR imaging in vivo, following trauma. As part of the study, we are modeling the kinetics of lesion enhancement in a longitudinal study of barrier disruption over weeks. 2) Also we are using diffusion tensor imaging to map fiber tracts in highly structured white matter in nervous tissue and have recently extended this procedure to allow fiber tracking in the gray matter of the spinal cord. 3) We are constructing unique RF coils for implantation near the region of interest. These chronically implanted coils are inductively coupled to an external coil during measurements and provide a gain as large as a factor of 4 in signal-to-noise ratio. Because of the gains possible, these coils allow the acquisition of very spatial resolution MR images and spectra.
Requirements: Undergraduate chemistry and physics (with calculus)
Starting Date: open
Ending Date: ongoing
Academic Year Positions: one
Summer Positions: one
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Andre, P. Mauderli
Field of Research: Neural mechanisms of pain
Phone Number: 352-392-9538
E-mail: AMauderli@dental.ufl.edu
Project Description: The research is conducted in human participants and focuses on how chronic pain diseases, such as fibromyalgia syndrome, irritable bowel syndrome, myofascial pain syndrome, and traumatic brain injury affect pain sensitivity, pain modulation and the relative unpleasantness of pain. The response properties of the neural mechanisms that mediate pain are probed with thermal stimuli, and the participants rate the sensation elicited by the stimuli on a visual analog scale.
Requirements: The applicant must be interested in neural mechanisms of pain, communicate well with our study participants and be willing to spend time in the lab on a regular basis. Computer skills are advantageous.
Starting Date: anytime
Ending Date: anytime
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Julie Maupin-Furlow
Field of Research: Microbiology
Phone Number: 352-392-4095
E-mail: jmaupin@ufl.edu
Project Description: Structure and Function of Archaeal Proteases. Archaea are a metabolically diverse group of bacteria, many of which survive in extreme environmental conditions such as hydrothermal vents and the Dead Sea. The main objective of this study is to determine how the archaea use proteases in global regulatory networks to maintain quality control of proteins for survival. To achieve this objective we are using genetic, molecular, and biochemical methods. Thermophilic Gram-positive Biocatalysts for Biomass Conversion to Ethanol Escherichia coli and other Gram-negative bacteria have been genetically modified to produce ethanol efficiently from biomass using the pyruvate decarboxylase and alcohol dehydrogenase genes from Zymomonas mobilis. However, Gram-positive bacteria are hardier at high temperature and low pH and, thus, more economical for the metabolic engineering of industrial-scale ethanol production. The main objective of this study is to engineer a homo-ethanol pathway into thermophilic Gram-positive bacteria.
Requirements: Basic knowledge of microbiology. Strong commitment to and adequate time for a research experience (2 semesters commitment is desirable).
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Julie Maupin-Furlow
Field of Research: Microbiology
Phone Number: 352-392-4095
E-mail: jmaupin@ufl.edu
Project Description: I. Structure and Function of Archaeal Proteases. Archaea are a metabolically diverse group of bacteria, many of which survive in extreme environmental conditions such as hydrothermal vents and the Dead Sea. The main objective of this study is to determine how the archaea use proteases in global regulatory networks to maintain quality control of proteins for survival. To achieve this objective we are using genetic, molecular, and biochemical methods. II. Thermophilic Gram-positive Biocatalysts for Biomass Conversion to Ethanol. Escherichia coli and other Gram-negative bacteria have been genetically modified to produce ethanol efficiently from biomass using the pyruvate decarboxylase and alcohol dehydrogenase genes from Zymomonas mobilis. However, Gram-positive bacteria are hardier at high temperature and low pH and, thus, more economical for the metabolic engineering of industrial-scale ethanol production. The main objective of this study is to engineer a homo-ethanol pathway into thermophilic Gram-positive bacteria.
Requirements: Basic knowledge of microbiology. Strong commitment to and adequate time for a research experience (2 semesters commitment is desirable).
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Paul Mislevy
Field of Research: Agronomey
Phone Number: 863-735-1314
E-mail: pmislevy@mail.ifas.ufl.edu
Project Description: Project ONA-03726 Title: Evaluation of Forage Gemplasm and Forage Management Practices. Evaluate promising forage plant germplasm for adaptaion, persistence, forage yield, qualily, seed production, responce to clipping or grazing management, herbicides etc.
Requirements: Research is conducted at the UF Range Cattle Research and Education Center, Ona, Florida. This center is located 180 miles south of Gainesville. Therefore applicants will need to live on the center or in a nearby town and have an automobile for transportation. This project requires applicants to work entirely in the field conducting applied research cutting plants, moving cattle from pasture to pasture etc. This would lend itself best for summer employment.
Starting Date: May 15, 2003
Ending Date: September 1, 2002
Academic Year Positions: 0
Summer Positions: 1
Independent Study: Not Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Laurence Morel
Field of Research: Immunogenetics
Phone Number: 392-2676
E-mail: morel@pathology.ufl.edu
Project Description: To characterize the genetic contribution of various chromosomal regions to Systemic Lupus Erythematosus (SLE) in a mouse model. Our research combines various techniques of molecular genetics and immunology to correlate the presentation of various autoimmune abnormalities with specific genetic backgrounds generated through selective mouse breeding.
Requirements: A strong commitment to research and some background in molecular biology and/or immunology.
Starting Date: any
Ending Date: any
Academic Year Positions: 1-2
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Connie Mulligan
Field of Research: Human molecular genetics
Phone Number: 392-2253, x 248
E-mail: mulligan@anthro.ufl.edu
Project Description: Genetic variants that are associated with alcohol dependence and related disorders or effects such as binging, flushing, or antisocial personality disorder are being investigated. Questions of interest include the use of recent methods to detect variants with small effect on the disease and the relationship between the presumed protective effect of flushing and prevalence of alcohol dependence. Assayed variants occur in alcohol metabolism genes (ADH, ALDH) and neurological response genes (opioid, seratonin, and dopamine receptors). Native Americans suffer a disproportionately high rate of alcohol dependence relative to other U.S. populations and several populations have agreed to participate in our study.
Requirements: Strong commitment to and adequate time for a research experience (at least 2 semesters commitment is desirable). Some basic lab experience is required and knowledge of PCR and agarose gel electrophoresis is a plus.
Starting Date: Open
Ending Date: Open
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Required
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Connie Mulligan
Field of Research: Human molecular genetics
Phone Number: 392-2253, x 248
E-mail: mulligan@anthro.ufl.edu
Project Description: We are analyzing molecular genetic variation in human populations located throughout the Horn of Africa and the Arabian peninsula to test hypotheses concerning migrations across the Red Sea and the evolution of language and food production methods. This region of the world is known to be important for the emergence of anatomically modern humans, but it is also important for more recent evolution. We are interested in determining the origin and directionality of migrations across the Red Sea and the evolution of the Afro-Asiatic language family. Mitochondrial, X and Y, and autosomal genes and variants are assayed in order to address these questions. Specific regions of interest include Ethiopia, Eritrea, Oman and Yemen. Additional countries will be included as the project develops.
Requirements: Strong commitment to and adequate time for a research experience (at least 2 semesters commitment is desirable). Some basic lab experience is required and knowledge of PCR and agarose gel electrophoresis is a plus.
Starting Date: Open
Ending Date: Open
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Required
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Josef Neu, M.D.
Field of Research: Neonatal Nutritional Biochemistry and Developmental Gastroenterology
Phone Number: 392-4195
E-mail: neuj@peds.ufl.edu
Project Description: Nutrition and the GI environment in the neonate have major effects not only during infancy, but for the entire lifetime of the individual, and this can even span generations due to epigenetic effects. Our lab has several ongoing projects that involve the requirements for certain amino acids such as glutamine and arginine in very low birthweight infants, the effect of various nutrients on subsequent development of Type 1 and Type 2 diabetes, the effect of the intestinal commnensal microflora and probiotics on intestinal development, and the effects of novel nutritional agents on retinal diseases such as retinopathy of prematurity. Our work spans from evaluation of basic mechanisms of nutrients in cell cultures, studies in animal models and translation of these to and from studies in human infants.
Requirements: Strong science background. Biochemistry course and some lab experience very helpful.
Starting Date: open ended
Ending Date: open ended
Academic Year Positions: Yes
Summer Positions: Yes
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Harry S. Nick
Field of Research: Biochemistry and Molecular Biology
Phone Number: 392-3303
E-mail: hnick@ufl.edu
Project Description: Our laboratory's research focuses on understanding how mammalian genes are turned on and off by cell and tissue-specific mechanisms. We utilize advanced techniques in molecular biology to study molecular mechanisms which control how genes are regulated, by understanding the organization of chromatin structure and studying protein-DNA interactions. Research has focused on proteins that exhibit both pro- and anti-inflammatory activities in the lung, spinal cord, kidney, and intestine. These genes include: manganese superoxide dismutase (MnSOD), a potent cyto protective anti-oxidant protein; the inducible nitric oxide synthase (iNOS) gene which generates elevated levels of the powerful neurotransmitter and vasodilator, nitric oxide (NO); cytoplasmic phospholipase A2 (cPLA2) which controls intracellular levels of arachidonate metabolites and heme oxygenase, the enzyme responsible for heme degradation and the sole source of the signal molecule, carbon monoxide. These genes are also linked through transcriptional regulation by a subset of pro-inflammatory mediators, including bacterial endotoxin (LPS), interleukin 1 (IL-1), tumor necrosis factor (TNF-alpha) and interferon-gamma as well as a variety of cellular stress signals. The ultimate goals are to understand the mechanisms controlling gene regulation in an effort to modulate gene expression patterns to develop therapeutic strategies that affect outcome in appropriate disease pathologies.
Requirements: Undergraduate Biology minimum, some knowledge of molecular biology preferred
Starting Date: open
Ending Date: open
Academic Year Positions: 1-2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Prof. Max Nickerson
Field of Research: Herpetology
Phone Number: 352 392 6581
E-mail: maxn@flmnh.ufl.edu
Project Description: The Florida Museum of Natural History's Division of Herpetology maintains major archival research collections of preserved amphibians and reptiles that provide a regional base for research on systematic biology of these species, their morphology, ecology, behavior, distribution and conservation. Assistance is needed in cataloguing, sorting, and labelling specimens, in arranging the collections on the shelves, and in classifying the reprint library.
Requirements: An interest in reptiles, amphibians, wildlife, zoology, biology, natural history, systematics, taxonomy, biological diversity, wild species, or environmental science. Though not required, Library Sciences skills would be an asset.
Starting Date: 1 September 1999
Ending Date: ongoing
Academic Year Positions: Variable
Summer Positions: Variable
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Juan C Nino
Field of Research: Materials Science and Engineering
Phone Number: 352-846-3787
E-mail: jnino@mse.ufl.edu
Project Description: BIOCERAMIC SCAFFOLDS FOR TISSUE ENGINEERING- Bone diseases and injuries are serious conditions that have a significant impact on the quality of life of an individual. Most of the materials used today have too many disadvantages and can still be much improved. he objective of this proposal is to develop of a new class of bioactive ceramics with good mechanical properties by investigating the bioactivity and mechanical properties of selected pyrochlore compositions.
Requirements:
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Lucia Notterpek
Field of Research: Inherited peripheral neurodegeneration
Phone Number: 294-0030
E-mail: notterp@mbi.ufl.edu
Project Description: The overall interests of the laboratory are the cellular interactions of neurons and glia during the development of the nervous system and how these processes are altered in disease. A key element for normal neuronal functioning is myelination, the glial ensheathment of axonal processes that serves to facilitate signal propagation from the neuronal cell body to the synaptic terminal. A glial molecule, termed PMP22, has been shown to have a key role in normal nerve development, since point mutations, deletions or duplications of the PMP22 gene are associated with nerve degeneration and disease. It is the main goal of my laboratory to define the roles of PMP22 in the peripheral nervous system and in the pathogenesis of neuromuscular disorders. Various in vivo and in vitro model systems are available in the laboratory to examine how alterations in PMP22 gene expression lead to abnormal myelination and subsequent axonal degeneration.
Requirements: Strong interest in basic biomedical research.
Starting Date: open
Ending Date: open
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Thomas O'Brien
Field of Research:
Phone Number: 392-6878
E-mail: tobrien@ufl.edu, http://www.med.ufl.edu/biochem/tobrien/index.html
Project Description: Our studies have shown that mammalian mitochondria contain unusual ribosomes that differ structurally and functionally from other ribosomes. These ribosomes are products of two separate genomes, and they appear to be evolving more rapidly than other ribosomes. We are using affinity probes, immunologic, and biochemical approaches to study their organization and unique functional properties. Available projects include: 1) Molecular cloning of cDNA and genes for mammalian mitochondrial ribosomal proteins; 2) Computer analysis of protein sequence, structure and evolution; 3) Computer modeling of ribosomal structure (RNA and proteins); 4) Function of GTP-binding protein; enzymatic studies.
Requirements:
Starting Date: current
Ending Date: ongoing
Academic Year Positions: 2-3
Summer Positions: 2-3
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: David Oppenheimer
Field of Research: Plant Cell Biology
Phone Number: 352-273-8105
E-mail: doppen@botany.ufl.edu
Project Description: REGULATION OF ACTIN ORGANIZATION IN PLANTS This project focuses on the newly discovered RAP proteins in plants. RAP proteins control actin organization by interacting with Actin Depolymerizing Factor (ADF), a key regulator of actin dynamics. As part of an interdisciplinary approach to the function of RAPs, we are using genetics (mutant isolation), molecular biology (gene cloning), biochemistry (in vitro protein expression), and cell biology (confocal microscopy) methods. Most of this work is carried out using the plant, Arabidopsis thaliana, because the complete genome sequence is available and insertion mutants exist for a large fraction of the known genes. The immediate goal of this project is to determine the interactions between specific RAP and ADF family members using genetic and biochemical assays.
Requirements: Undergraduate biology and chemistry
Starting Date: continuing
Ending Date:
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Larry Page
Field of Research: Ichthyology
Phone Number: 392-1721, ext. 483
E-mail: lpage1@ufl.edu
Project Description: The Ichthyology Division of the Florida Museum of Natural History has several ongoing research projects on freshwater fishes, including an inventory of catfishes of the world, and geographic variation and evolutionary relationships among several taxonomic groups. Opportunities to participate in one or more of these research projects are available to undergraduates majoring in, or otherwise particularly interested in, biology.
Requirements: Requirements: Students majoring in, or otherwise particularly interested in, biology should contact Larry Page for an interview.
Starting Date: open
Ending Date: open
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Linda Papa
Field of Research: Clinical/ Medical
Phone Number: (352) 265-5911
E-mail: lpstat@aol.com
Project Description: Background: Each year, emergency departments treat a million adults with “minor head injury”. About 6% of these patients have some acute injury on computed tomography (CT scan) and 0.5% have an injury requiring surgery. Objectives: To compare and assess the accuracy of 2 clinical decision guidelines (the Canadian CT Head Rule and the the New Orleans criteria) for predicting ‘need for neurological intervention’ and for detecting ‘clinically important brain injury’ on CT. Importance: This clinical study of mild traumatic brain injured patients is an essential step in the development of an accurate, reliable, and clinically sensible decision rule for physicians to use. These CT Head Rules will permit physicians to standardize care of these patients and diminish the risk of missing serious injuries.
Requirements: Knowledge of some medical terminology. Medical background helpful but not necessary. Motivated and willing to learn. Study ongoing in Gainesville and Jacksonville.
Starting Date: variable
Ending Date: variable
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Linda Papa
Field of Research: Clinical/ Medical
Phone Number: (352) 265-5911
E-mail: lpstat@aol.com
Project Description: Cognitive Outcome Predictors in the Emergency Department for Mild Traumatic Brain Injury (TBI) Background: Mild TBI has been termed the 'silent epidemic' of our times. Since most patients manifest no gross neurological disturbance at the time of their injury it is difficult to predict who will develop complications. Objectives: This study will prospectively determine the incidence of cognitive and social dysfunction after mild TBI and predict which patients will develop cognitive and social function deficits after injury so that early follow-up and treatment could be instituted.
Requirements: Knowledge of some medical terminology. Motivated and willing to learn. Medical background helpful but not necessary.
Starting Date: variable
Ending Date: variable
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Susan Percival
Field of Research: Nutritional Sciences
Phone Number: 392-1991
E-mail: percival@ufl.edu
Project Description: This laboratory studies dietary factors that influence the immune system and inhibit carcinogenesis. Our research uses cell culture, mice and humans to investigate the mechanisms by which dietary factors such as phytochemicals in grape and grape products, mango, guava and passionfruit enhance or suppress immunity and inhibit the process of cancer.
Requirements: Completion of organic chemistry series and lab. Analytical chemistry preferred. Nutritional Sciences student preferred.
Starting Date: none
Ending Date: none
Academic Year Positions: varies
Summer Positions: varies
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Deidre Pereira
Field of Research: Health Psychology
Phone Number:
E-mail: dpereira@phhp.ufl.ed
Project Description: This project examines relations among psychosocial factors, heat shock protein (HSP) 70, and cytokines in women with early stage endometrial cancer.
Requirements: Required: Introduction to Psychology Preferred: Research Methods and Statistics (or similar course)
Starting Date: 01/01/2004
Ending Date: 12/31/2004
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Deidre Pereira
Field of Research: Health Psychology
Phone Number:
E-mail: dpereira@phhp.ufl.edu
Project Description: This project examines relations among psychosocial factors, heat shock protein (HSP) 70, and cytokines in women with early stage endometrial cancer.
Requirements: Required: Introduction to Psychology Preferred: Research Methods and Statistics (or similar course)
Starting Date: 01/01/2004
Ending Date: 12/31/2004
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: William Perlstein
Field of Research: Clinical-Cognitive Neuroscience
Phone Number: 265-0680 x 46846
E-mail: wmp@grove.ufl.edu
Project Description: The Clinical-Cognitive Neuroscience Laboratory focuses on studying mechanims of high-level cognition, as well as affective influences on cognition, in healthy subjects and in subjects with a number of psychiatric and neurologic disorders and aging. Research methods vary depending upon the questions addressed, and include functional magnetic resonance imaging (fMRI), high-density event-related potentials (ERPs), and computerized tasks. Student may participate in many phases of the research, and responsibilities will include data collection, assistance with data analysis and participant scheduling. Students will gain a well-rounded experience in all aspects of research design and planning, as well as clinical-cognitive neuroscience theory and methods. The experience will form an outstanding foundation for those interested in graduate or medical education with an emphasis on clinical-cognitive neuroscience.
Requirements: Interest in cognitive neuroscience and psychopathology, 3.4 GPA, good 'people' skills, and a willingness to learn. Minimum of 2 credits per semester (6 hours/week). Committment of 2 semesters is desirable.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-3
Summer Positions: 1-3
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Andrew Piercy
Field of Research: Biology, Ichthyology
Phone Number: 392-2360
E-mail: apiercy@flmnh.ufl.edu or tsford@flmnh.ufl.edu
Project Description: The Florida Program for Shark Research at the Florida Museum of Natural History is seeking volunteers/independent study students for ongoing shark life history projects. Duties will include preparing shark reproductive tissues for examination, cleaning of shark vertebrae for age and growth analysis, and preparing shark jaws for tooth morphology studies. These are multiyear studies and volunteers may subsequently become eligible for part-time employment. Chances for students to earn academic credit through independent study and/or the University Scholars program will be addressed on an individual basis.
Requirements: We are looking for motivated students interested in sharks. Experience with sharks is not required as students will be trained in the necessary skills. Serious students may contact Travis Ford or Andrew Piercy for an interview.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: varies
Summer Positions: varies
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Ann Progulske-Fox
Field of Research: oral biology
Phone Number: 846-0770
E-mail: apfox@dental.ufl.edu
Project Description: The student will be working in a molecular microbiology laboratory. The research is centered around the study of genes and gene products suspected of playing major roles in the disease processes of known human oral pathogens. It has been proposed that some oral pathogens may play an important role in the causation of systemic disease, also. Specific projects are ongoing and therefore subject to change. Projects may be basic in nature or they may involve an applied approach, for instance, the development of a vaccine or other therapies for periodontal disease.
Requirements: a laboratory class in basic microbiology and sterile technique a class in molecular biology preferred ability to maintain a somewhat flexible schedule, for instance, to be able to work in the the evening to finish and experiment
Starting Date: any time
Ending Date:
Academic Year Positions: 2-3
Summer Positions: 2-3
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Daniel L. Purich
Field of Research: Biochemistry and Molecular Biology
Phone Number: 392-9410
E-mail:
Project Description: Microtubules play central roles in cell motility, mitosis, and specialization, and my primary research goal is to understand such processes at the molecular level. Ultimately, every aspect of microtubule action (including self-assembly, coordination with other cellular organelles, and effective regulation) will be related to the unique structural and chemical properties of the microtubule proteins. We seek to identify and to characterize these molecular design properties by borrowing, combining, and extending techniques in biophysics, enzymology, and cell biology with the further intent to provide an integrated molecular and cellular perspective.
Requirements:
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study:
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Principal Investigator: Francis Putz
Field of Research: Plant Ecology
Phone Number: 392-1486
E-mail: fep@botany.ufl.edu
Project Description: Pith is the cylindrical column of tissue in the center of the stems of most plants. It typically consists of thin walled parenchyma cells surrounded by a ring of xylem (woody tissue). In most species pith is low in tissue density but solid, whereas in some monocots (e.g., bamboo) and dicots (e.g., Cecropia), it is hollow except at the nodes. Additionally, some species (e.g., some members of the Juglandaceae) have a distinctive chambered pith with numerous partitions and cavities. While bark, xylem, leaves, and roots have attracted a great deal of attention from researchers interested in plant form and function, the ecology of pith is a little explored topic. Although pith comprises only a small portion of the plant body, it may play a number of ecological roles. This research project will test some basic hypotheses related to pith such as: 1. Pith diameter increases with increasing leaf size. 2. Pith diameter is largest in the stems of woody vines (i.e, lianas), next largest in shrub stems, and narrowest in tree stems.
Requirements: Interest in plant anatomy and microscopy are needed, but more critical is intense interest in understanding how plants work.
Starting Date: any time
Ending Date: any time
Academic Year Positions: 1
Summer Positions: 0
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: K.H. Quesenberry
Field of Research: Plant Breeding and Genetics
Phone Number: 392-1811
E-mail: clover@gnv.ifas.ufl.edu
Project Description: Ongoing projects involving classical and current genetic techniques (including genetic transformation) to investigate the effects of various genes on pest resistance, persistence, and yield of clovers and other forage legumes.
Requirements: Inquisitive mind, hard working, interest in plant science, prefer academic background of basic genetics and experience with sterile techniques.
Starting Date: ASAP
Ending Date: Variable
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Krestin Radonovich
Field of Research: Autism
Phone Number: 392-7928
E-mail: kradonov@psychiatry.ufl.edu
Project Description: The purpose of this study is to learn more about the nature of motor and cognitive problems in children with autism and related developmental disorders. Studies have shown that as many as 50-100% of individuals with autistic disorders demonstrate some type of motor impairment; motor problems seen in children with autism can include: clumsiness, coordination problems, and poor balance. Subtle motor impairments can often be the first indication of an emerging developmental disorder. The goal of the proposed research is to link impairments in motor functioning with specific types of cognitive functioning in young children with autism. The reason for this is that if we can more accurately identify problems in very young children, we can make better prognostic decisions, and begin implementing appropriate treatments early.
Requirements: Applicants should have experience working with young children and be comfortable interacting with sometimes very challenging children. Hours of commitment vary depending upon the students' goals and the researchers' current needs.
Starting Date: immediate
Ending Date: ongoing
Academic Year Positions: TBD
Summer Positions: TBD
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Bala Rathinasabapathi
Field of Research: Plant Biology
Phone Number: 352-392-3991
E-mail: brath@mail.ifas.ufl.edu
Project Description: Antioxidant Phytochemicals in Fruits. Project I Blueberries are known for their antioxidant qualities. The blue pigment in the berries is an anthocyanin. Certain varieties of Blueberries, including a recently released Florida variety 'Florida Rose', lack this blue pigment. The aim of this project is to compare Blueberry varieties differing in their pigment profiles, for their potential differences in their antioxidant qualities. The research will involve laboratory work such as grinding berries and running chemical analyses for their antioxidant properties and pigment composition. Project II. Flavonoid glycosides are antioxidant phytochemicals commonly found in a number of plants. Citrus species are especially rich in these compounds. Our recent research shows that Citrus leaves contain significantly larger quantities of antioxidant flavonoid glycosides than fruits. The objective of this research is to evaluate individual flavonoid compounds commonly found in Citrus for their antioxidant abilities.
Requirements: Motivation required. Atleast 8 hrs per week required for one semester. Some quantitative skills would help but not required. Some familiarity with lab methods would help but not required.
Starting Date: Any time
Ending Date: Any time
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Roger Reep
Field of Research: Neuroscience
Phone Number: 392-4700 x 3859
E-mail: reep@mbi.ufl.edu
Project Description: Rat model of hemispatial neglect: we are investigating neural circuitry related to neglect, a mysterious cognitive dysfunction that usually occurs in ~40% of humans after strokes in the right hemisphere of the brain. We are using special antibodies to encourage neural sprouting as a possible therapeutic treatment. Manatee brain organization: we are mapping sensory regions of the nervous system using specialized stains. We are also studying the neural organization and behavioral capacity of an unusual system of tactile hairs found all over the body.
Requirements: Scientific curiosity, good verbal communication, able to work well with others, get your hands dirty.
Starting Date: any time
Ending Date: any time
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: L Douglas Ried
Field of Research: Pharmacoepidemiology
Phone Number: 352-273-6259
E-mail: ried@cop.ufl.edu
Project Description: This project is an ongoing study of the relationship between second generation antipsychotics and weight gain, hyperglycemia, and hyperlipidemia.
Requirements: Medical science background and interest in pharmacy/pharmacoepidemiology. Student should be a junior or senior. Pharmacy student preferred.
Starting Date: Anytime
Ending Date: Anytime
Academic Year Positions: One
Summer Positions: One
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Daniel Robinson
Field of Research: Pharmacy
Phone Number: 352-273-6240
E-mail: robinson@cop.ufl.edu
Project Description: Database and monitoring tool for pharmacy students, faculty and practitioners for drug therapy of commonly seen medical conditions and diseases, e.g. hypercholesterolemia, hypertension, diabetes, depression, etc. Data includes patient demographics, disease state history, medication profiles, medication adherence information, recommendations to improve drug therapy management and cost savings.
Requirements: Working knowledge of Microsoft Access. Preference given to those with healthcare training and/or experience.
Starting Date: anytime
Ending Date: open
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Neil Rowland
Field of Research: Psychobiology
Phone Number: 352-392-0601 ext 287
E-mail: nrowland@ufl.edu
Project Description: Students are involved in studies on the neurobiological mechanisms underlying food and fluid intake. Our research involves the use of rats or mice, and the experiments range from behavioral, pharmacological, through neuroanatomical and other measurements on tissue. Current projects focus on genetic and environmental aspects of obesity, early life events and subsequent food or alcohol choice, sodium appetite, and models of nicotine use and prevention.
Requirements: A minimum of either general chemistry, general biology, or physiological psychology. Should not have known allergy to animal dander.
Starting Date: Any time
Ending Date:
Academic Year Positions: up to 3
Summer Positions: up to 3
Independent Study: Required
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Don Samuelson
Field of Research: Veterinary Medicine
Phone Number: 392-4700 ext 5754
E-mail: samuelsond@mail.vetmed.ufl.edu
Project Description: We are examining the histology of the Florida manatee for development of an internet atlas. In addition to performing microanatomical analysis of different organ systems, various histochemical and immunohistochemical procedures will be used to establish functional-structural correlates. The collected information will be placed on a website.
Requirements: Interests in veterinary medicine, medicine, marine biology, and/or zoology with appropriate foundation courses for pre-vet, pre-med, or zoology programs.
Starting Date: May 2006
Ending Date: April 2007 or beyond
Academic Year Positions: 2
Summer Positions: 1-2
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Justin Sanchez
Field of Research: Biomedical Engineering
Phone Number: 352-392-4827
E-mail: sanchjc@peds.ufl.edu
Project Description: The goal of the NRG is to develop state-of-the-art novel medical treatments by operating at the interface between basic neural engineering research and clinical care. This direction of research is motivated by the potential of direct neural interfaces for delivering therapy and restoring functionality to disabled individuals using engineering principles. Two clinical outcomes of the lab’s mission are to restore movement to the paralyzed and control epileptic seizures. The mechanism by which we can achieve these outcomes is through the sampling of large ensembles of cells from the cortex and deep brain structures, from which we have a window of opportunity to study the functional relationships of neural systems (motor system, limbic system). The process of transitioning this technology into a clinically useful device will require two parallel paths of research. In the first path, experimental paradigms involving microelectrode array recordings in behaving animals will be developed in conjunction with signal processing techniques for studying the unknown aspects of neural coding and functional neurophysiology. These signal processing techniques will then be implemented in portable, low-power, wireless hardware (electrodes, DSPs) that is feasible for a clinical implementation of a BMI. The second path, high-density array ECoG recordings in humans, provides a less invasive technique for neural interfaces however it still remains unknown how to extract BMI control signatures that are sufficiently spatially and temporally resolved. Moreover, it will be critical to obtain feedback about interactions of the individual’s intent and the engineered interface; a necessary condition for improving the performance of the interface. Ultimately, it will take the culmination of new functional neurophysiologic knowledge, clinical interaction, signal processing, and low-power, portable electronics to demonstrate the clinical utility for human subjects.
Requirements:
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Michael Scharf
Field of Research: Insect Toxicology / Molecular Biology
Phone Number: 392-1901
E-mail: mescharf@ufl.edu
Project Description: This project involves the evaluation of various test chemicals and hormones on termite development and caste differentiation. The goal of this work is to characterize biological chemicals produced by termites that regulate their caste composition, as well as to evaluate novel chemicals that may be used to disrupt caste composition in termite colonies. Student responsibilities will consist of making termite collections from on-campus field sites, maintenance of laboratory insect colonies, making dilutions and solutions of test materials, setting up and running laboratory assays/experiments, conducting investigations of gene and protein expression in response to chemical treatments, and keeping a thorough laboratory notebook. At the end of the project period, the student will be required to write a detailed report of their experimental findings, interpretations and conclusions, in journal article format.
Requirements: >15 combined credit hours of course work in biology, zoology, entomololgy, chemistry, and/or biochemistry. Previous laboratory coursework/experience is also highly desirable, as well as a strong motivation to ask questions and work independently.
Starting Date: Jan 2007
Ending Date: Dec 2007
Academic Year Positions: 1
Summer Positions: 1-3, depending on grant funding
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Not Available

Principal Investigator: Gregory Schultz, Ph. D.
Field of Research: Biochemistry, Molecular Biology, Gene Therapy, Wound Healing
Phone Number: 392-4060
E-mail: schultzg@obgyn.med.ufl.edu
Project Description: Wound healing is a complex biological process involving the integrated actions of cytokines, growth factors, proteases and receptors. My laboratory is investigating ways to modulate wound healing using transient expression of genes delivered to wound cells by plasmids and virus vectors. Undergraduate students would work with graduate students and post-doctoral fellows on projects that include cloning and sequencing growth factor genes, constructing antisense plasmids, and measuring levels of proteases in wound biopsies.
Requirements: Biology, organic chemistry, physics, biochemistry (helpful), calculus (helpful). Students should be highly motivated, dependable and able to work in groups.
Starting Date: current
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Geralyn M. Schulz, Ph.D.
Field of Research: Speech Pathology, Treatment Efficacy
Phone Number: 392-2041
E-mail: schulz@cpd.ufl.edu
Project Description: The acoustic characteristics of Parkinson's patients is assessed pre and post pallidotomy surgery. This surgery has been shown to be effective in relieving limb motor signs of tremor and rigidity but the effects on the voice and speech of these patients has yet to established. This project is being conducted in collaboration with the departments of Neurology and Neurosurgery, Shands Hospital.
Requirements: An acoustics course would be helpful, plus the regular requirements necessary for participation in the Undergraduates Honors Program or permission of Principle Investigator.
Starting Date: 9/1/96
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Jiunn-Jye Sheu
Field of Research: Health Education and Behavior
Phone Number: 352-3920853 ext 1310
E-mail: jjsheu@hhp.ufl.edu
Project Description: This project is to establish a multimedia database for health education implementation. The participant will learn how to search multimedia and enter a team of database establishment.
Requirements: Health education major or minor
Starting Date: any time
Ending Date: at least one month
Academic Year Positions: no limit
Summer Positions: no limit
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: David Silverman
Field of Research: Biochemistry
Phone Number: 392 3556
E-mail: silvermn@college.med.ufl.edu
Project Description: Work in Dr. Silverman's lab includes investigations of the mechanisms of very efficient enzymes, mainly human carbonic anhydrase and human superoxide dismutase. These enzymes contain metal ions such as zinc and manganese. Part of our research aims at understanding the role of such metals in the catalysis. Other research aims to show how these important enzymes are limited in overall catalysis by proton transfer steps. This includes intermolecular proton transfers between the enzymes and solution and intramolecular proton transfer between residues of the enzyme itself. The emphasis of the lab includes structure-functions studies using site-directed mutagenesis of carbonic anhydrase and superoxide dismutase. Methods used to characterize the catalysis of these variants are mass spectrometry, stopped-flow spectrophotometry, and pulse radiolysis. In addition, nuclear magnetic resonance, electron spin resonance, and X-ray crystallography are used to obtain structural information on the mutant enzymes.
Requirements: A background in chemistry would be useful, general and organic chemistry especially.
Starting Date: Open
Ending Date: Open
Academic Year Positions: One
Summer Positions: One
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Rosalia Simmen
Field of Research: Animal Molecular Biol
Phone Number: 392-2185
E-mail: simmen@animal.ufl.edu
Project Description: Please see my website at http://www.animal.ufl.edu/simmen
Requirements: The applicant should be a rising undergrad senior with interest in obtaining lab experience in molecular and cell biology as it pertains to animal sceince and biomedical research. He/she should be academically strong in the sciences and should have a GPA commensurate with an Honors student (GPA of 3.8 or better).
Starting Date: anytime
Ending Date:
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Amy Simonne
Field of Research: Food Safety and Quality
Phone Number: 352-392-1895 x 232
E-mail: asim@ufl.edu
Project Description: Tropical culinary herbs and spices are often used for enhancing food flavor and fragrance, preserving foods as well as for their medicinal properties. Preservative power of herbs and spices may due to the anti-microbial compounds that are presence within the plants. Further, some tropical herbs/spices have been documented to have Anti-diarrheal and other therapeutic properties. This project seeks to explore and evaluate, and characterize functional ingredients (flavor compounds, antioxidative and antimicrobial properties) from under utilized tropical culinary herbs. Potential students will be involved in the following activities: 1) to screen tropical herbs for antimicrobial activity against common foodborne pathogens; 2) to screen for antioxidative property tropical herbs extracts; 3) characterize flavor compounds, and, 4) to evaluate the efficacy of the antimicrobial property as well as the antioxidative powers in selected food model systems.
Requirements: This project has room for motivated students with chemistry, or biology and microbiology and related major with lab experience. Strong commitment to, and adequate time for, research (minimum two semesters to one year) is preferable. Students must be willing to commit a minimum of 15-20 hours a week to the project and perform in a mature and professional manner. Upper classmen (junior/senior) preferred, but exceptions can be made. Please provide current college transcript.
Starting Date: on going/flexible
Ending Date: on going/flexible
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Meera Sitharam
Field of Research: Computer Science and Mathematics
Phone Number: 352 392 1260
E-mail: sitharam@cise.ufl.edu
Project Description: Below, I describe 4 research projects suitable to undergrads. Introduction to Projects 1, 2, 3: Declarative Geometric Computation and Nanoscale Applications Declarative geometry (DG) specifies a composite of simple interacting geometric primitives by declaring the properties that the composite should possess. Applications of DG are diverse, and include solid modeling, engineering design, molecular modeling, virtual reality, robotics, geometry theorem proving. Geometric constraints are usually a part of most DG frameworks. Our FRONTIER geometric constraint solver (demoed at Solid Modeling 2001 and available as GNU software) is based on the new constraint decomposition and recombination (DR) planner which avoids blind and extensive algebraic-numeric equation solving by taking advantage of underlying geometry. Our DR-planner excels with respect to several performance measures. I am currently developing a new game theory and geometric constraint based framework for declarative geometry (DG). FRONTIER is expected to provide the base for the implementation of this DG framework. Currently under investigation are the following applications of the new DG framework: modeling nanoscale phenomena such as viral self assembly and other macromolecular self assemblies and deriving geometric computational inspiration from these processes; There are 4 of my graduate students and one REU undergraduate currently involved in all aspects of the theory, development and implementation of the new DG framework atop FRONTIER. Furthermore, the interdisciplinary nature of the 3 applications could potentially involve working with the collaborating faculty member, graduate students, postdocs and REU's in the biochemistry, molecular biology, and mechanical engineering departments. Project 1. 3d sketcher for Nanoscale Declarative Geometry applications Both 2d and 3d sketchers are crucial parts of the implementation of any DG framework. The sketchers are essential for demonstrating the flexibility and features offered by the new DG framework. The sketcher also should mesh with the existing software including existing 2d and 3d sketchers. Furthermore, the sketcher should be adaptible to different applications for which FRONTIER is employed. This project is accessible to undergraduates and will provide experience at focused interdisciplinary collaboration, developing code starting from a rough vernacular specification, organizing modular, portable and extendible code, as well as rapidly acquiring versatility with graphics languages and platforms. Project 2. Fundamental algorithmic questions from the new declarative geometric framework Several fundamental algorithmic questions arise from the new DG framework. For example: how to extract a minimal set of constraints from given example conformations of the geometric compostite; how to find atleast one realization of an underconstrained geometric composite; how to avoid the use of a full-fledged algebraic-numeric solver in the case of parameterless constraints, how to classify and navigate through solution conformations based, perhaps on characteristics of an input sketch; and how to design a simple geometric game whose equilibria correspond to the optima of a given global function. This project would expose the student to design and analysis of combinatorial geometric algorithms, through easily accessible, and intuitive computational geometry, game theory, and sometimes graph problems. The student requires little formal background to start tackling these problems from first priniciples and intuition developed from sketching a few examples. Project 3. Implementing the new Declarative Geometry framework atop FRONTIER for Nanoscale applications FRONTIER's main innards (besides the sketcher) are the decomposition-recombination (DR) planner and a so called Equation/Solution manager (ESM) which serves as not only as a flexible parser to convert constraints to equations but also coordinates FRONTIER's calls (dictated by the DR-planner's output) to an algebraic-numeric solver and helps navigate through various conformations of the specified geometric composite. To implement the new game-theoretic declarative geometry framework, new algorithms need to be coded, i.e, conceptually well-defined modules need to be written to augment both the DR planner and the ESM. Moreover, we need to handle specific augmentations required by the particular application under consideration. The project is accessible to undergraduates and will expose the student to the process of understanding a few interacting algorithms, implementing one or two of them, designing appropriate data structures, and tailoring the implementation of the data structure in a suitable manner to fit into existing code, as well as algebraic-numeric software packages. Project 4. Symmetry, Invariants and Complexity lower bounds This concerns 2 of my projects that deal with the role of symmetry and other geometric and algebraic invariants in proving complexity lower bounds, ``hardness'' results, in particular for so-called non-naturalizing proofs -- the only type of proof that holds any promise at proving P not equal NP. One of the projects is geometric in nature, and involves giving a lower bound on the dimension where certain types of hyperplane arrangements or geometric designs can live. The second is algebraic in nature and concerns what (shapes of zero-sets) special polynomial systems can achieve. Both types of problems interface with the theoretical questions from Project 2 above, are of independent interest outside complexity theory, for example in the nanoscale applications of Projects 1,2,3 above, i.e, in characterizing the limits of biogeometric phenomena such as the macromolecular self-organization. Both problems have fixed parameter versions that are unsolved, tractable (large combinatorial puzzles), and good, minimal solutions are likely to give intuition necessary for generalization to arbitrary parameter values. Both problems lend themselves to a highly intuitive treatment starting from first principles and small computational examples. 3 undergrads (heading for double math/cs majors) have worked on this type of project with me, and have done well. Their work has resulted in a publication.
Requirements: General training required for Projects 1, 2,3,4 Note that specific skills required for each of the projects is given below. For all the projects below, it would be advisable for the student to have: data structures, discrete mathematics and linear algebra courses, although spatial reasoning capabilities and geometric intuition could substitute for some of the course requirements. Specific training required for Project 1 Java programming experience Specific training required for Project 2 What is required is a theoretical and analytic bent as well as an interest in the design and analysis of algorithms. It would also be advisable, though not necessary for the student to have a java programming background, so that quick implementations could be done to check theoretical concepts and ideas. It would help if the student had some native interest in game based models of self-organization (artificial life etc.) Specific requirements for Project 3 C++ programing background. Java would be advisable but not necessary. Specific requirements for Project 4 This project is for someone who has no difficulty with proofs and has some degree of mathematical maturity, and is definitely theoretically inclined. Discrete Math and Linear Algebra courses are a necessity. Some type of programming experience would be useful. It would help if the student has a popular sciece level of interest in complexity.
Starting Date: any time in 2002-03
Ending Date: atleast one year from starting date
Academic Year Positions: 2-3
Summer Positions: 2-3
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Chelsea Smartt
Field of Research: Molecular Biology and Biochemistry
Phone Number: 772-778-7200x156
E-mail: ctsmart@ufl.edu
Project Description: Mosquitoes require blood for oogenesis. This requirement results in the spread of diseases that impact human health. The research being conducted in my laboratory investigates interactions between Cx. nigripalpus and Cx. quinquefasciatus mosquitoes with West Nile virus (WNV) and Ae. albopictus mosquitoes with Dengue virus (DENV). Specifically, we are analyzing the proteins and controlling genetic factors produced by the midgut and salivary glands whose expression is altered by WNV and DENV exposure.
Requirements: General Biology and Chemistry.
Starting Date: 1/03/07
Ending Date:
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Arun Srivastava
Field of Research: Gene Therapy
Phone Number: 386-462-4090
E-mail: asrivastava@gtc.ufl.edu
Project Description: The project involves a human virus, which does not cause any disease in humans, to be used as a vector for gene therapy of a sickle-cell disease, beta-thalassemia, liver cancer, and erythroleukemia
Requirements: Background in molecular biology
Starting Date: Flexible
Ending Date: Negotiable
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Available
Salary: Available
Volunteer: Not Available

Principal Investigator: Roland Staud
Field of Research: Pain Research
Phone Number: 392-4681
E-mail: staudr@ufl.edu
Project Description: Functional neuroimaging with Positron Emission Tomography (PET) and functional magnetic resonance imaging (fMRI) have begun to provide new insights into the cortical and subcortical processing of pain. These techniques can measure alterations in cerebral blood flow, which reflect changes in neuronal activity. The brain areas identified to be relevant to pain processing in human subjects include the thalamus, primary and secondary somatosensory cortex (S1, S2) the anterior insula and the anterior cingulate cortex. Previous results of wind-up testing in subjects with fibromyalgia syndrome (FMS) showed signs of central sensitization as well as abnormalities of temporal summation of second pain when compared to normal controls. The proposed study will evaluate the brain activation of FMS and NC subjects during wind-up testing. FMS patients will undergo measurements of clinical pain and wind-up during fMRI. The quantitative methods of evaluation involve the use of a validated visual analogue scale (VAS) for measuring clinical pain as well as repetitive application of brief, non-injurious thermal and mechanical stimulation that normally produces a moderate degree of temporal summation of sensation intensity. The subjects will verbally rate the magnitude of late sensations elicited by each stimulus, using a numerical scale.
Requirements:
Starting Date: 3/1/02
Ending Date: open ended
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Roland Staud
Field of Research: Modulation of Tonic Muscle Pain Attenuates Overall Clinical Pain of Fibromyalgia Patients
Phone Number: 392-4681
E-mail: staudr@ufl.edu
Project Description: Pain intensity encoding in human subjects is determined by stimulus intensity and spatial summation. Relevant spinal cord neurons related to pain encoding are the so-called wide-dynamic range neurons (WDR neurons). These neurons receive sensory input from the periphery, i.e. skin and/or deep tissues. Although much is known about pain coding of phasic nociceptive stimuli, less data is available for the role of tonic pain stimuli. Tonic pain stimuli are clinically relevant because they represent the cause of many types of clinical pain, including back pain, headaches, etc. Therefore tonic nociceptive mechanical stimulation may represent an important mechanism for clinical pain. Research Plan: We have built an apparatus that can apply exact mechanical pressure to the skin and deep tissue of study subjects. A read-out is used for adjusting stimulus intensity. Careful regulated pneumatic pressure is used to deliver the stimuli to the subjects. Pain intensity will be modified by injection of 1% lidocaine (local anesthetic) or placebo. Normal controls (NC) and subjects with musculoskeletal pain will be used for these studies. Standard pressure stimuli will be applied to subjects' shoulder muscles. Visual analogue pain scales will be used to register experimental pain ratings. Central pain processing will be tested using heat stimuli to the upper and lower extremities. A power analysis of preliminary data indicated that only 10 NC and pain subjects will be needed for statistical analysis. This project will answer the important question whether decreasing intensity of local muscle pain represents a meaningfully approach for pain reduction.
Requirements: Most importantly, interest in human pain research. Biology background, familiarity with computers, and lab experience are helpful but not necessary.
Starting Date: January 2003
Ending Date: open ended
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Ruth Steiner
Field of Research: transportation
Phone Number:
E-mail:
Project Description: This research involves the coordination of land use and transportation, and the development of indicators to measure sustainable transportation that can be applied internationally. In the current debate about the sprawling of cities, the regulation of land development and the building of transportation infrastructure are of utmost importance. Historically, the tools for planning our transportation system have focused on accomodating the automobile. This research involves identifying innovative techniques that are being used to coordinate land use and transportation with a focus on other modes of transportation (bicycle, pedestrian and transit). Students working on this research will be required to conduct research in the library, on the internet and by telephone calls to planning practitioners. Students will be required to assist in researching and writing a literature review and summaries of research findings.
Requirements: A desire to learn and a curiosity about the subject are of great importance to this position. Students should have solid writing and presentation skills, strong research and critical thinking skills, be a good member of a team, and be reliable and dependable. Graphic (both drawing and computer) and cartographic skills are a plus.
Starting Date: open
Ending Date: Fall 2006
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Eric Storch
Field of Research: Childhood Obsessive-Compulsive Disorder; Tourette's Disorder
Phone Number: 392-3611
E-mail: estorch@psychiatry.ufl.edu
Project Description: These projects seek to investigate new methods of assessing symptoms and impairment in children with Obsessive-compulsive disorder (OCD) and tourette's disorder. There are also opportunities to conduct senior theses in this lab.
Requirements: Psychology major; GPA > 3.5 in major. Junior or Senior preferred
Starting Date: 2/1/05
Ending Date: 12/30/05
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Yasu Takano
Field of Research: Physics
Phone Number: 392-8499, 392-8869
E-mail: takano@phys.ufl.edu
Project Description: Project title: heat capacity of low-dimensional antiferromagnets at low temperatures Antiferromagnets are solids in which the magnetic dipole moments of neighboring atoms prefer to align antiparallel to each other. In some antiferromagnets, the dipole moments form a two dimensional or one dimensional arrays rather than three-dimensional periodic structures. Low-temperature properties of such low-dimensional antiferromagnets are poorly understood and are the subjects of many experimental and theoretical studies at the moment. In this project, the student will measure the heat capacity of novel low-dimensional antiferromagnets at temperatures below 10 K to gain microscopic understanding of their macroscopic properties near the absolute zero temperature. The student will become familiar with experimental techniques at low temperatures, and use of computers in data acquisition and data analysis, as well as modern theory of magnetism and thermal physics.
Requirements: Must be a major in physical science or engineering and have at least taken two semesters of introductory physics at a university.
Starting Date: May 1, 2004
Ending Date: September 30, 2006
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Naohiro Terada
Field of Research: Stem Cell Biology
Phone Number: 392-2696
E-mail: terada@pathology.ufl.edu
Project Description: Ongoing projects developing methods for directing differentiation of mouse embryonic stem cells towards functional somatic cells such as hepatocytes and cardiomyocytes, using biomaterial scaffoldings, signal modifying reagents, small molecules etc.
Requirements: Basic knowledge of molecular and cellular biology. Strong commitment to research. Students are expected to spend at least 10 hrs a week, over one year.
Starting Date: Open
Ending Date: Variable
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Fred Thompson
Field of Research: Invertebrate zoology/malacology
Phone Number: 352-392-1721
E-mail: fgt@flmnh.ufl.edu
Project Description: The current project involves Mexican landsnails of the genus Holospira. These are desert inhabiting organisms that have undergone extensive local evolution and speciation. About 100 species are known, representing fewer than 25% of the estimated number of species. Many additional discoveries wait to be made in the deserts of northern Mexico. This project involves making these species known, and placing them into an evolutionary context. Their environment is undergoing severe degradation. Conservation measure require that these species be properly classified prior to when conservation measure can be enacted.
Requirements: Careful attetion to details.
Starting Date: January, 2006
Ending Date: August, 2006
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Roger Tran-Son-Tay
Field of Research: Biomedical Engineering
Phone Number: 352 392 6229
E-mail: rtst@ufl.edu
Project Description: We would like to develop a flow chamber using an air-liquid two-phase flow. This flow chamber would then be used to study the mechanical and rheological properties of cells.
Requirements:
Starting Date:
Ending Date:
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: C. Eduardo Vallejos
Field of Research: Genetics, Plant Molecular Biology
Phone Number: 392-1928 x 321
E-mail: vallejos@ufl.edu
Project Description: We have constructed a genetic linkage map of the common bean with hybridization-based DNA markers. These markers are know as RFLP which stands for restriction fragment length polymorphisms; although RFLPs are the most reliable type of marker, they are expensive and laborious to obtain. The objective of this project is convert these markers into PCR-based markers, which are easy and relatively inexpensive to analyze. Towards this end, all 220 clones for RFLP markers have been sequenced, and PCR-suitable primers have been obtained to amplify the corresponding sequences. We need to survey the PCR amplification products for polymorphisms among different cultivated and wild accessions of the common bean. Results from these efforts can be easily coupled with other projects aimed at the genetic mapping of various genes that control resistance to potyviruses.
Requirements: I would like to considered students that are willing to commit to working on one of these projects for at least one semester. Some background in general biology and genetics or biochemistry, and previous lab experience are desirable, but not essential.
Starting Date: 9/1/05
Ending Date: 8/31/06
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Required
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Margaret (Peggy) Wallace
Field of Research: genetics
Phone Number: 352-392-3055
E-mail: peggyw@ufl.edu
Project Description: Various aspects of human molecular genetics are studied in the laboratory. Primarily this involves projects aimed at mutation analysis of genes known to cause hereditary disease such as neurofibromatosis type 1, and projects to identify disease genes that have not yet been characterized, such as cardiomyopathy. We also study disorders and human traits that are not controlled by single genes (multifactorial traits, such as vitiligo), trying to find genetic polymorphisms that can contribute to susceptibility to that disorder.
Requirements: Biological science background, must be available for labwork at least 10 hours per week, preferably available during summers as well. Some familiarity with genetics or molecular biology is helpful.
Starting Date: variable
Ending Date: variable
Academic Year Positions: 1-2
Summer Positions: 0-1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Keith White
Field of Research: Psychology
Phone Number: 392-0601x219
E-mail: kdwhite@ufl.edu
Project Description: This research involves perceptual alternation, its brain mechanisms, and how these differ in selected populations. Perceptual alternation happens when stimuli can be seen in more than one way, such as a drawing that looks briefly like a vase but then switches to look like two faces. Magnetic resornance imaging studies are underway to identify processes in the brain which fluctuate with time courses like the perceptual switching. Other studies compare these time courses in various subjects; patients with bipolar or schizophrenic disorders, adults with a history of 'lazy eye', and non-patient groups of various ages.
Requirements: Requirements: Students who have taken physiological psychology and/or sensory processes courses, or their equivalents. Knowledge about computers is a plus. Ending Date: Academic Year Positions: 4 Summer Positions: 4 Independent Study: Available Work Study: Not Available Salary: Not Available Volunteer: Available
Starting Date: Any
Ending Date:
Academic Year Positions: 4
Summer Positions: 4
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Keith White
Field of Research: Psychology
Phone Number: 392-0601x219
E-mail: kdwhite@ufl.edu
Project Description: This research on neuroplasticity involves functional magnetic resornance imaging to identify processes in the brain which change as stroke patients recover functions during their rehabilitation.
Requirements: Requirements: Students who have taken neuropsychology, physiological psychology and/or sensory processes courses, or their equivalents. Knowledge about computers is a plus.
Starting Date: Any
Ending Date:
Academic Year Positions: 4
Summer Positions: 4
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Faculty of the Whitney Lab
Field of Research:
Phone Number:
E-mail:
Project Description: Please see our web site at http://whitney.ufl.edu
Requirements:
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study:
Work Study:
Salary:
Volunteer:

Principal Investigator: Keith Willmott
Field of Research: Insect systematics, evolution, conservation
Phone Number: 846 2000 x 484
E-mail: kwillmott@flmnh.ufl.edu
Project Description: The tropical Andean region contains the richest and most poorly known butterfly fauna in the world, and is a potentially ideal area for studying the origins of montane faunas, the importance of forest refugia in diversification, and processes underlying latitudinal and elevational gradients in species richness and turnover. I am currently involved in a long-term study of the diversity, distribution and conservation of the butterflies of Ecuador, as well as a new project on the butterflies of the tropical Andean region, from Venezuela to Bolivia. Work will take place at the Florida Museum of Natural History, one of the world's largest collections of butterflies. Activities include helping with identification of specimens and curation of the collection, databasing information from specimen labels and literature using a Microsoft Access database, photographing examples of each species to provide images for a web archive, and preparing dried, papered specimens for incorporation into the collection. Students can expect to learn a variety of techniques used in museum curation as well as gain a broader understanding of neotropical diversity.
Requirements: Students should be committed to working for a minimum of 4 hours per week for at least one semester, though hours are flexible. Students should be hard-working, careful, prepared to work alone after training, have experience in working with computers and have a keen interest in zoology. Some knowledge of biological classification and Spanish would also be helpful.
Starting Date: January 2007
Ending Date: ongoing
Academic Year Positions: open
Summer Positions: open
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Charles Wood
Field of Research: Fetal Physiology
Phone Number: 392-4488
E-mail: woodc@ufl.edu
Project Description: This is a project designed to identify the neuroendocrine mechanisms controlling the fetal responses to stress (hypotension, hypoxia). The work involves measurement of hormones in fetal plasma, detection of the expression of enzymes and hormones in tissues using molecular biological tools, and investigation using in vivo models. The long-term objective of this work is to develop a better understanding of fetal stress (which is life-threatening in human beings) and to develop tools for preventing fetal stress and preterm birth.
Requirements: Undergraduate biology, chemistry, and mathematics.
Starting Date: 5/1/04
Ending Date: 8/30/05
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Shen-Ling Xia
Field of Research: Renal Physiology/Cell Biology/Biophysics
Phone Number: 352-392-4008
E-mail: xiasl@medicine.ufl.edu
Project Description: Our laboratory is primarily interested in renal physiology with the research focus in 1) intercellular and intracellular calcium signaling transduction pathways; 2) ligand-gated ion channels in the renal cell; 3) purinergic signaling in renal regulation and its impact to hypertension; and 4) non-neuronal catecholamine in the collecting duct Na transport. One project suitable for undergraduate in life sciences is aimed at investigating ATP-activated signaling pathway in the renal cation transport process. This research makes use of not only cellular/molecular biology techniques, but also biophysical techniques such as short circuit measurements and electrophysiology recordings. The student who makes a significant contribution to on-going project can expect to be included as a co-author of publication.
Requirements: Background in life science preferred and contact Dr. Xia for further details.
Starting Date: Flexible
Ending Date: Flexible
Academic Year Positions: 1-2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Daniel Zarin
Field of Research: Restoration Ecology
Phone Number: NA
E-mail: treeguy@ufl.edu
Project Description: The Chief investigator for this project is Daniel Zarin PhD and the primary contact person is Brian Daley, (treeguy@ufl.edu). The project involves the restoration of degraded sites in the US Virgin Islands to native forest (potentially value enhanced) through the control of the invasive Leucaena leococephala and introduction of native tree seedlings. Research sites are comprised primarily of abandoned agricultural and pasture land, a rapidly growing cover type in the territory.
Requirements: The student should either have a strong background in ecology or Geographic information systems. The student should also be able to work in the field under the challenging summer conditions of the Virgin Islands in difficult to access areas. Work will include but is not mimited to; data collection of understory composition, canopy structure/composition, survey of the soil seed bank in degraded sites, recording way point in a GPS and some data entry. The student will most likely work closely with the lead field researcher and a student from the university of the virgin islands. This means that in addition to having the abiltiy to successfully work alone, the student will need to be a contributing member of a field team. This is a new position and, as such, is still flexible. Interested parties should contact Brian Daley at treeguy@ufl.edu.
Starting Date: summer 2004, (flexible)
Ending Date: Summer 2004
Academic Year Positions: 0
Summer Positions: 2
Independent Study: Not Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Issam Zineh
Field of Research: Cardiovascular Disease and Pharmacogenetics
Phone Number: 352-273-6184
E-mail: zineh@cop.ufl.edu
Project Description: Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis The aims of this study are to characterize the systemic immunomodulatory effects of atorvastatin in patients who are currently recommended for lifestyle modifications, but not drug treatment, based on consensus guidelines for the management of dyslipidemia. In addition, genetic variation as a contributor to variability in immunomodulatory response in this population is explored. Students will perform lab work related to the genetic hypotheses.
Requirements: Commitment to participation in a research project Attendance at all scheduled activities (e.g., seminars, journal club,and research meetings). Submission of a written abstract of research Oral presentation of research
Starting Date: Open
Ending Date: Open
Academic Year Positions: TBD
Summer Positions: TBD
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available