Return to the Research Homepage

Medical and Biomedical Sciences

Principal Investigator: John Aris
Field of Research: Aging
Phone Number: 392-1873
E-mail: johnaris@ufl.edu
Project Description: Molecular and Cellular Basis of Aging Our laboratory is interested in the molecular and cellular basis for aging. There are a number of mechanisms at the molecular and cellular levels that contribute to the aging process, including, but not limited to: (1) genomic instability; (2) reactive oxygen species (ROS) damage; and (3) impaired repair pathways. Genomic instability includes loss and rearrangement of genetic information in cells. For example, in baker’s yeast, recombination within the repetitive ribosomal DNA (rDNA) locus give rise to extrachromosomal rDNA circles (ERCs) that are linked to the aging process. We are currently interested in understanding the mechanism(s) by which ERCs reduce life span. We use yeast as an experimental system because of the ease of using various approaches in biochemistry, cell biology, genetics, and molecular biology. Our overall goal is to pursue mechanisms that regulate life span in yeast cells and extend these studies to higher cells types in order to better understand general mechanisms that influence aging at the molecular and cellular levels.
Requirements: Basic knowledge of biology and genetics. Strong commitment to, and adequate time for, research (minimum one semester). Upper classmen (junior/senior) preferred, but exceptions can be made.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: John Aris
Field of Research: Aging
Phone Number: 392-1873
E-mail: johnaris@ufl.edu
Project Description: Molecular and Cellular Basis of Aging -- Our laboratory is interested in the molecular and cellular basis for aging. There are a number of mechanisms at the molecular and cellular levels that contribute to the aging process, including, but not limited to: (1) genomic instability; (2) reactive oxygen species (ROS) damage; and (3) impaired repair pathways. Genomic instability includes loss and rearrangement of genetic information in cells. For example, in baker’s yeast, recombination within the repetitive ribosomal DNA (rDNA) locus give rise to extrachromosomal rDNA circles (ERCs) that are linked to the aging process. We are currently interested in understanding the mechanism(s) by which ERCs reduce life span. We use yeast as an experimental system because of the ease of using various approaches in biochemistry, cell biology, genetics, and molecular biology. Our overall goal is to pursue mechanisms that regulate life span in yeast cells and extend these studies to higher cells types in order to better understand general mechanisms that influence aging at the molecular and cellular levels.
Requirements: Basic knowledge of biology and genetics. Strong commitment to, and adequate time for, research (minimum one semester). Upper classmen (junior/senior) preferred, but exceptions can be made.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Roland Aud
Field of Research: Pain
Phone Number: 273-5343
E-mail: staudr@ufl.edu
Project Description: Pain is a complex experience and almost always requires acitvation of nociceptors. However, in many pain syndromes such activation is not readily detectable. Low back pain and fibromyalgia are such pain disorders. This research project will examine the role of tonic nociceptive input on chronic pain in patients with fibromyalgia syndrome. Age/sex matched participants will be used as normal controls. Tonic pain will be induced by muscle stimulation and reduced by muscle injection with a local anesthetic. Psychophysical testing of the skin and muscle via computerized thermal/mechanical probes will be used to examine the role of tonic mechanical stimulations on pain and pain processing. In a subsequent study the same manipulations will be used during functional magnetic resonance scans (fMRI) to characterize the pain related brain areas related to tonic impulse input.
Requirements:
Starting Date: 2005
Ending Date: open
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Shirley Baker
Field of Research: Invertebrate Ecology and Physiology
Phone Number: 392-9617 x264
E-mail: smbaker@ifas.ufl.edu
Project Description: The selected student will assist with various aspects of field and laboratory research related to the CLAMMRS Project. Projects this summer include 1) Measuring currents and spatial and temporal variability in environmental parameters (temperature, salinity, oxygen, etc.) at clam grow-out sites, 2) Completing physiological tolerance experiments in the lab, and 3) Measuring energy budgets of clams. We will provide the student with a variety of field and laboratory research experiences; the student will also be involved in projects on invasive invertebrates, bivalve feeding and bivalve genetics.
Requirements: Location: NW Gainesville, Millhopper Road (transportation required)
Starting Date: May 1, negotiable
Ending Date: negotiable
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Russel M. Bauer
Field of Research: Neuropsychology
Phone Number: 273-6455
E-mail: rbauer@phhp.ufl.edu
Project Description: Develop protocols for early detection of dementia
Requirements: some psychology background
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-3
Summer Positions: contact faculty mentor
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Russell M. Bauer
Field of Research: Neuropsychology
Phone Number: 273-6455
E-mail: rbauer@phhp.ufl.edu
Project Description: Evaluate cognitive effects of epilepsy and of surgical interventions for epilepsy relief.
Requirements: some psychology background
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-3
Summer Positions: contact faculty mentor
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Andrea Behrman
Field of Research: Physical Therapsy
Phone Number: 273-6116
E-mail: abehrman@phhp.ufl.edu
Project Description: The purpose of this study is to compare the effects of robotic- versus manually-assisted locomotor training on walking ability in adults with incomplete spinal cord injury. The purpose of a second study is to pilot a training protocol to improve the recovery of walking in persons post-stroke.
Requirements: Demonstrate initiative and is responsible. Basic computer skills. Background in psychology, biology, exercise science, biomechanics, or motor learning may be most appropriate. Availability during particular hours for training subjects, as well as a flexible schedule for working on data sets and video logs.
Starting Date: March, 2005
Ending Date: March, 2008
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Dr. Steve Borst
Field of Research: Pharmacology
Phone Number: 374-6114
E-mail: seborst@ufl.edu
Project Description: My lab is interested in studying the loss of muscle mass and strength that occurs as a part of the aging process and in testing strategies for reversing those losses. Age is accompanied by changes in the growth hormone and insulin pathways. We study the effects in aged rats of 1) growth hormone and related hormones, 2) antidiabetic agents and/or 3) exercise training. You will have the chance to learn exercise traning performance techniques, assays of hormones and mRNA, measurement of body composition and measurement of responses to insulin.
Requirements: Background in biological science and sufficient time to participate in a project.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1B
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Peggy Borum
Field of Research: Clinical Nutrition
Phone Number: 352-392-7553
E-mail: prb@ufl.edu
Project Description: There are positions available for undergraduate students with a desire to be involved in a meaningful research experience. These projects emphasize independent, critical and creative thinking. The research lab is composed of three research teams. The Gator Team works with children who are HIV positive. There are patient care concerns as well as gathering nutritional and body composition data for clinical studies. The Carnitine Team studies the long-chain fatty acid carrier, carnitine, by working with animal models and analyzing data gathered in both human and animal studies. The KetoGator Team works with children participating in Ketogenic Therapy for seizures, which is a dietary alternative to anticonvulsant medications. There is an emphasis on patient care and gathering data for clinical studies. Members of all three teams make up the InvestiGators. InvestiGators is a research-based honor society that provides students who are involved in intensive research a forum to practice good research procedure, share knowledge, and foster friendships (http://borum.ifas.ufl.edu/Investigators/). Undergraduate students with adequate commitment to the project have opportunities to be involved in either patient interaction or bench research. With time, there is a potential for leadership positions and personal thesis projects.
Requirements: Students must be willing to commit a minimum of 15-20 hours a week for a minimum of 1 year to the project and perform in a mature and professional manner.
Starting Date: Anytime
Ending Date: Anytime
Academic Year Positions: Flexible
Summer Positions: Flexible
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Dawn Bowers
Field of Research: Neuropsychology
Phone Number: 392-3450
E-mail: dbowers@hp.ufl.edu
Project Description: My lab focuses on the neuropsychology of emotion, memory, and higher order cognition in normals and patients with various neurologic and/or psychiatric disorders. This is a multidisciplinary laboratory in cognitive neuroscience/ clinical neuropsychology. We conduct studies across the lifespan(children to adults). Research methods vary from paper & pencil to more technologically complex (e.g., transcranial magnetic stimulation, psychophysiology, neuroimaging, priming, face digitizing, computerized tasks). Students get well-rounded research experience and the opportunity to learn more about graduate school or medical school. Most undergrads in my lab go on to graduate school (clinical psychology, neuroscience) or medical school. For more information, you can check out my lab's website at: www.hp.ufl.edu/cogneuro
Requirements: Some psychology and statistics are required; GPA of 3.4; curiosity and willingness to learn, attention to detail coupled with good people skills; Minimum of 3 credits per semester (8-10 hours/week), including one hour for weekly lab meetings. Committment of at least 2 semesters in desirable.
Starting Date: anytime
Ending Date: varies
Academic Year Positions: 1-3
Summer Positions: 1-3
Independent Study: Required
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Marc Branch
Field of Research: behavioral pharmacology
Phone Number: 392-0601 x205
E-mail: branch@ufl.edu
Project Description: Discovery and characterization of behavioral/experiential factors that determine whether an animal's behavior reveals tolerance or sensitization (or neither) in the face of repeated exposure to psychoactive drugs. Undergrad activities involve either behavioral observations, data-analysis, or both.
Requirements: Interest in behavior.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2 to 3
Summer Positions: 2 to 3
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Mark Brantly
Field of Research: Genetics/Cell Biology
Phone Number: 352-846-0752
E-mail: brantml@medicine.ufl.edu
Project Description: Identify novel mutations in the Alpha-1-antitrypsin gene (SERPINA1) using a combination of high resolutions DNA melting and DNA sequencing
Requirements: must have completed basic genetics courses and be available 20 hrs/week
Starting Date: 9/1/05
Ending Date: 8/30/06
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Mark Brantly
Field of Research: Genetics/Cell Biology
Phone Number: 352-846-0752
E-mail: brantml@medicine.ufl.edu
Project Description: Evaluate and map the unfolded protein response in cells expressing the a mutant form of alpha-1-antitrypsin (SERPINA1)
Requirements: must have complete basic cell biology courses
Starting Date: 9/1/05
Ending Date: 8/30/06
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Daniel Brazeau
Field of Research: Population biology/Genetics
Phone Number: 392-5016
E-mail: dbrazeau@biotech.ufl.edu
Project Description: The laboratory is part of the Molecular Services Core within the Interdisciplinary Center for Biotechnology Research at UF. The role of the BEECS Genetic Analysis Lab is to assist ecologists, and evolutionary and conservation biologists in taking advantage of the wide variety of molecular markers now available for field and laboratory studies. Projects include 1) population genetics of corals, scrub lizards, rattlesnakes, sea turtles, viscachas; 2) Paternity analysis in soft and stony corals, crickets, weaverbirds, mole salamanders; 3) Phylogenetic studies of rattlesnakes, striped newts, sirens, and 4) DNA Wildlife Forensics
Requirements: Basic knowledge of biology and a willingness to work in a lab
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Adriaan Bruijnzeel
Field of Research: Drug dependence
Phone Number: (352) 328-9793
E-mail: awbruijn@psychiatry.ufl.edu
Project Description: The aim of this project is to develop novel treatments for nicotine dependence. Abrupt cessation of tobacco smoking has been shown to induce depression and anxiety. It has been hypothesized that these symptons contribute to relapse. This projects focuses on the development of pharmacotherapies for the depressive-like signs of nicotine withdrawal using rodent intracranial self-stimulation. Abrupt cessation of nicotine administration has been shown to decrease the postive reinforcing effects of intracranial self-stimulation (i.e., deficit in brain reward function). This project will investigate the effects of novel drug treatments on the depressive-like signs of nicotine withdrawal.
Requirements: Projects are time consuming, but the student can learn numerous new techniques, including surgeries. This project is only suitable for students with a strong interest in preclinical biomedical research.
Starting Date: 08/18/05
Ending Date:
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Emilio Bruna
Field of Research: Ecology
Phone Number: 846-0634
E-mail: brunae@wec.ufl.edu
Project Description: We study (1) the diversity and abundance of invertebrates (especially ants) in local ecosystems, (2) plant-animal interactions, especially ant-plant protection mutualisms, and (3) the effect of human activities such as habitat fragmentation and the disruption of natural fire regimes on plant-animal interactions and plant population ecology. These projects involve field, lab, or computer work, (for example, sample collection, insect identification, field experiments, computer models, GIS analysis). There is the potential for future independent projects. For a description of the lab's projects see www.wec.ufl.edu/faculty/brunae.
Requirements: Depending on the project, previous training in ecology, entomology, GIS, matrix algebra, or MATLAB is helpful. However, no experience is necessary - all you need is an interest in ecology and a willingness to learn new things.
Starting Date: Anytime
Ending Date: 3 month commitment
Academic Year Positions: open
Summer Positions: open
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Michael Bubb, Assoc. Prof
Field of Research: Immunology/Cell Biology/Biophysics
Phone Number: (352) 392-4681
E-mail: bubbmr@medicine.ufl.edu
Project Description: Cells undergo programmed cell death or apoptosis as a normal physiologic or developmental response; abnormalities in this process result in significant pathology relevant to both the immune system and to the development of cancer. Our laboratory has been investigating the role of the actin cytoskeleton in apoptosis. This student project will entail the study of the mechanism by which apoptosis is induced when marine natural products alter the actin cytoskeleton. The student can expect to be included as an author of publications that include his or her results. A more complete description of our lab's research can be found at: http://www.medicine.ufl.edu/rheuma/bubb.shtml
Requirements: Please provide current college transcript. Background that includes laboratory coursework in molecular biology and/or cell biology and/or immunology would be helpful. Salary available for general laboratory maintenance responsibilities and activities.
Starting Date: Spring or Summer 2003-2004
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Michael Bubb, Assoc. Prof
Field of Research: Neuroscience/Cell Biology/Biophysics
Phone Number: (352) 392-4681
E-mail: bubbmr@medicine.ufl.edu
Project Description: Memory formation and retention require remodeling of neuronal architecture. Our laboratory investigates the role of the actin cytoskeleton in this remodeling process, which we believe is the structural basis for synaptic plasticity. This student project will entail the study of the mechanism by which actin-regulatory proteins control neuronal architecture at the level of the synapse. The student can expect to be included as an author of publication that include his or her results. A more complete description of our lab's research can be found at: http://www.medicine.ufl.edu/rheuma/bubb.shtml
Requirements: Please provide current college transcript. Background that include laboratory coursework in molecular biology and/or cell biology and/or biochemistry would be helpful. Salary available for general laboratory maintenance responsibilities and activities.
Starting Date: Spring or summer 2003-2004
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: George Burgess
Field of Research: Biology: Ichthyology
Phone Number: 392-2360
E-mail: gburgess@flmnh.ufl.edu
Project Description: The International Shark Attack File is a compilation of all known shark attacks that is administered by the American Elasmobranch Society, a professional organization comprised of international workers studying sharks, skates and rays, and the Florida Museum of Natural History. The File is utilized by biological researchers and research physicians; access to the data is granted only after careful screening on a case-by-case basis. Access by the press and general public is strictly forbidden since much information is considered privileged. Many of the data in the File originate from the voluntary submissions of numerous cooperating scientists who serve worldwide as regional observers. Regional observers forward investigations of attacks in their areas for integration into the File. Data submitted to the File is screened, coded and computerized. Hard copy documentation, including original notes, press clippings, photographs, audio/video tapes, and medical/autopsy reports, is permanently archived. More than 2,700 individual investigations are currently housed in the International Shark Attack File, covering the period from mid-1500's to present. Requests for summary information and non-privileged data are made to the File's director. Selected students may utilize the database, under supervision of the director, to produce honors or independent studies OR they may work as volunteers in ongoing research projects.
Requirements: Serious students may contact George H. Burgess for an interview. Normally only upper division (junior or senior) students majoring in a biological science are considered, but exceptions may be made.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 3
Independent Study: Required
Work Study: Available
Salary: Not Available
Volunteer: Required

Principal Investigator: George Burgess
Field of Research: Biology: Ichthyology
Phone Number: 392-2360
E-mail: gburgess@flmnh.ufl.edu
Project Description: The ichthyological WebPages of the Florida Museum of Natural History has proven to be an extremely popular site among World Wide Web users. The shark and conservation sections are particularly well utilized. It is our goal to continually upgrade the site with distance learning material aimed at a variety of user groups, including secondary school students, recreational anglers, aquarists, and lay conservationists. We are happy to accept qualified students interested in biology, secondary education, and computers to participate development of educational ichthyological WebPages material and placement aboard our web site.
Requirements: Serious students may contact George H. Burgess for an interview. Normally only upper division (junior or senior) students majoring in a biological science, secondary shool education, or a computer field are considered, but exceptions may be made.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 3
Independent Study: Required
Work Study: Available
Salary: Not Available
Volunteer: Required

Principal Investigator: George Burgess
Field of Research: Biology: Ichthyology
Phone Number: 392-2360
E-mail: gburgess@flmnh.ufl.edu or apiercy@flmnh.ufl.edu
Project Description: The Florida Program for Shark Research at the Florida Museum of Natural History currently is studying life history attributes of several species of sharks. We are looking for volunteers/independent study students available at a minimum of 6 hrs per week. Duties will include preparing shark reproductive tissues for histological studies, vertebrae for age and growth analyses, and shark jaws for tooth morphology studies. Experience with sharks is not required and students will be trained in the necessary skills. This is a multiyear study and volunteers may subsequently become eligible for part-time employment. Chances for students to earn academic credit through Independent Study and/or the University Scholars program will be addressed on an individual basis. We are looking for motivated students.
Requirements: Serious students may contact George H. Burgess or Andrew Piercy for an interview. Normally upper division (junior or senior) students majoring in a biological science are most highly considered, but highly motivated underclass students are encouraged to apply.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 3
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Robert Burne
Field of Research: Microbiology/Molecular Biology
Phone Number: 392-4370
E-mail: rburne@dental.ufl.edu
Project Description: Molecular genetic aspects of microbial biofilm formation. Biofilms are adherent populations of microbes imbedded in a polymer matrix and adhering to a surface. Biofilm diseases are highly prevalent in humans and eradication of biofilms is a major challenge. We are using a Functional Genomics approach to identify genes that are essential for the formation of pathogenic biofilms by bacteria. Using genome sequence information and DNA microarrays, we have identified a variety of genes of as-yet-unknown function that are essential for maturation of biofilms and tolerance of environmental stress. This project involves a combination of recombinant DNA methodology, biochemistry, physiology and microbiology to understand how bacteria form structurally complex biofilms and to identify new targets for combating infectious agents.
Requirements: Courses in microbiology and molecular genetics are desirable.
Starting Date: Flexible
Ending Date: Flexible
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Marian L. Buszko
Field of Research: Biomedical
Phone Number: (352) 392-7203
E-mail: marian@ufl.edu
Project Description: In-vivo NMR studies of gene regulation and/or metabolic pathways. The work may involve genetic engineering to explore metabolic potential in bacteria and the effects of extreme environments. In-vivo NMR experiments will be conducted using the unique, Web-operated instrument developed at the IFAS NMR Laboratory and available at the address http://m110.ifas.ufl.edu
Requirements: Microbiology or related major
Starting Date: 5/1/98
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Veronika Butterweck
Field of Research: Herbal Medicines
Phone Number: 352-846-2470
E-mail: butterwk@cop.ufl.edu
Project Description: Grapefruit juice (GFJ), a beverage consumed in large quantities by many, contains compounds with a wide range of beneficial properties including anti-inflammatory and anti-tumor activity, inhibition of blood clots and strong antioxidant activity. However, unlike other citrus fruit juices, grapefruit juice interacts with a variety of prescription medications, raising the potential for concern. The project is designed to identify compounds from GFJ that might be responsible for the interactions. The project includes analytical work (e.g. HPLC analysis of compounds) and cell culture models
Requirements: Research skills, willingness to work in a team
Starting Date: 09/01/2005
Ending Date: 08/31/2007
Academic Year Positions: 0
Summer Positions: 2
Independent Study: Not Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Brian Cain
Field of Research: Biochemistry and Molecular Biology
Phone Number: 392-6473
E-mail: bcain@biochem.med.ufl.edu
Project Description: The two major areas of research in the laboratory focus on ion translocating ATPases. One project suitable for undergraduate chemistry and microbiology majors is aimed at investigating structure-function relationships in the bacterial F1F0 ATP synthase. This research makes very heavy use of modern molecular biology techniques, bacterial genetics and enzymology. Most experiments involve site-directed mutagenesis and biochemical methods. The second project investigates the regulation of the mammalian renal H,K-ATPase. Work in this area is most suitable for a student interested in molecular biology and gene regulation. Ongoing research makes use of mammalian tissue culture, reporter gene technology, microarrays and a wide variety of recombinant DNA and blotting methods.
Requirements: We prefer students in their sophomore or junior years. Students majoring in IDS-Biochemistry, Microbiology and Chemistry are the most appropriate people.
Starting Date: Sept 2002
Ending Date: open
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Edward Chan
Field of Research: Autoimmunity/Cell Biology
Phone Number:
E-mail: echan@ufl.edu
Project Description: Our laboratory is primarily interested in autoimmunity with the focus in autoantigens involved in systemic autoimmune diseases and cancer. We are interested in the molecular and cell biology of important macromolecules and subcellular organelles which have become autoimmune targets. Students may learn molecular biology how to express recombinant proteins using a bacterial and other expression systems, produce milligram amount of antigens, and develop immunological assays such as ELISA, Western blotting, etc. Other methods include combination of recombinant DNA, tissue culture, and immunofluroescence microscopy.
Requirements: Please provide current college transcript. Background that includes laboratory coursework in molecular biology, microbiology, cell biology, and/or immunology preferred.
Starting Date: Flexible
Ending Date: Flexible
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Thomas Crisman
Field of Research: Ecology
Phone Number: 352-846-2150
E-mail: marcgris@ufl.edu
Project Description: Our study focuses on the effects of forest management strategies on stream communities. Specifically we are examining changes in habitat patch type on invertebrate communities. Students on this project will be involved in both laboratory and field work. Laboratory work will involve sample processing and identification on aquatic macroinvertebrates. Further work may involve experiments on movement patterns of invertebrates and digital image analysis. Field work will include macroinvertebrate, periphyton and leaf litter sampling.
Requirements: Interest in aquatic ecology with preference for students experienced in invertebrate identification.
Starting Date: 3/26/2005
Ending Date: 4/20/2007
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: James Cuda
Field of Research: Weed Biological Control
Phone Number: 352-392-1901 x 126
E-mail: jcuda@ufl.edu
Project Description: 1. Classical Biological Control of the Invasive Weed Brazilian peppertree (Schinus terebinthifolius)in Florida. 2. Classical Biological Control of the Aquatic Weeds Hydrilla (Hydrilla verticillata) and Hygrophila (Hygrophila polysperma) in Florida.
Requirements: Courses and laboratory experience working with arthropods (insects and mites) and/or plants Flexible work schedule; willing to work on weekends
Starting Date: 1 October 2006
Ending Date: 30 September 2007
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Not Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Jesse Dallery
Field of Research: Behavioral Pharmacology
Phone Number: 392-0601 ext 276
E-mail: dallery@ufl.edu
Project Description: Laboratory and applied research on nicotine and smoking. Laboratory research on the effects of nicotine (and other drugs of abuse) on choice. Applied research on behavioral treatments for cigarette smoking.
Requirements: Interest in behavior.
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: John Dame
Field of Research: Molecular Microbiology
Phone Number: 392-4700 x 5818
E-mail: damej@mail.vetmed.ufl.edu
Project Description: The human malaria parasite, Plasmodium falciparum, is an intracellular parasite that infects 500 million people each year in tropical and subtropical areas of the world. No vaccine is available and antimalarial drugs are losing efficacy. We culture the asexual phase of the life cycle continuously in human red cells in vitro. Recently the genome of this parasite has been completely sequenced and new tools for genetic manipulation have been developed. We are using these genetic tools to identify, among the gene products predicted from the genome sequence, potential antimalarial drug targets. Currently, we are looking for assistance in our research on the DNA gyrase encoded in the genome.
Requirements: Upperlevel coursework in microbiology, molecular biology,and biochemistry. Sufficient time available each week to contribute reliablly to ongoing projects. Laboratory experience and demonstrated interest or experience in tropical diseases, parasitology, or continuous cell culture desired.
Starting Date: Immediately
Ending Date: Ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Jaret Daniels
Field of Research: Entomology/Conservation
Phone Number: 392-1901 ext. 121
E-mail: jcdnls@ufl.edu
Project Description: Conservation of the endangered Miami blue butterfly-one of the nation's rarest insects. The project involves various related laboratory and field research opportunities that focus on captive breeding and maintenance, organism reintroduction, molecular diversity and inbreeding depression, population biology, and ant-larval interactions. Research can be completed at UF as well as in a number of south Florida field locations and will involve direct interation with graduate students.
Requirements: Interest and background in biology. May involve occasional travel-depending on research project. Fexible hours.
Starting Date: 9/1/06
Ending Date: NA
Academic Year Positions: Not limited
Summer Positions: Not limited
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Jaret Daniels
Field of Research: Biology/Entomology
Phone Number: 392-1901 ext. 121
E-mail: jcdnls@ufl.edu
Project Description: The Florida Butterfly Monitoring Network (FBMN) is a statewide citizen scientist program that trains public volunteers and directly engages university scientists, zoological institution staff members, and conservation land managers in field-based conservation and education targeting butterflies. FBMN participants provide up-to-date information on Florida's diverse butterfly fauna. The data collected will be used to assess the distribution and population trends of both common and imperiled species. This information will facilitate the development of appropriate species’ conservation and management strategies. Students will help monitor butterflies on a number of conservation land areas in Alachua county and adjacent counties. Additional opportunities for education material development are available.
Requirements: Interest in biology a plus. Willingness to work in the field. Must have own transportation.
Starting Date: Anytime
Ending Date: No end date
Academic Year Positions: Not limited
Summer Positions: Not limited
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Ben Dunn
Field of Research: Protein Engineering
Phone Number: 352 392-3362
E-mail: bdunn@college.med.ufl.edu
Project Description: Multiple projects dealing with relation of structure/function of proteolytic enzymes (PRs). Use of molecular biology for site-specific mutogenesis, protein expression, enzyme kinetics. Projects: a) HIV PR b) Malaria PRs c) Human Cathepsins d) FIV PR e) protein inhibitors f) Chimeric Proteins and protein folding g) tuberculosis protease h) Serine PRs of bacteria and fungi. Preference given to students in their second year at UF.
Requirements: Organic Chemistry, Biology, Interest in Biochemistry
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3-5
Summer Positions: 3-5
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Rodney Edwards
Field of Research: Obstetrics/Infectious Diseases
Phone Number: 392-3306
E-mail: edwardsr@obgyn.ufl.edu
Project Description: Our research program is focused on infections in pregnancy, preterm delivery, and the interaction between these two topics. Currently, the work in our laboratory is centered around the study of genes and gene products responsible for the inflammatory response that is mounted against pathogens and is responsible for many preterm deliveries. In addition to basic science-type projects, our group also is engaged in clinical research.
Requirements: For laboratory-based projects, classes in basic microbiology, molecular biology, and laboratory instruction in sterile technique are a must. For clinical research projects, one must be able to work independently and have some experience with computer data entry. For either type of project, the student should be responsible, highly motivated, and able to maintain a flexible schedule.
Starting Date: variable
Ending Date: variable
Academic Year Positions:
Summer Positions:
Independent Study: Not Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Captive propagation and reintroduction of the endangered Miami Blue butterfly.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Captive propagation and reintroduction of the endangered Miami Blue butterfly.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Chromosome evolution in butterflies and moths.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Behavior of tropical butterflies in the Butterfly Rainforest facility (nocturnal social roosting aggregations; territoriality; courtship and mating; nectaring and fruit-feeding; sound production; etc.).
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Museum techniques with Lepidoptera (training in specimen preparation, curation, taxonomy and classification).
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Florida native wildflowers and butterfly gardening.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas Emmel
Field of Research: Biological Sciences
Phone Number: 392-5894
E-mail: tcemmel@flmnh.ufl.edu
Project Description: Greenhouse and shadehouse culture of larval host plants and adult nectar plants.
Requirements: Freshmen through Seniors eligible. Must be available at least 6 hours per week. Must be bright, inquisitive, self-starter, willing to commit to a semester-long project. Background in biology not required for some projects (our best research assistants have included many non-science majors).
Starting Date: August 2005
Ending Date: Open
Academic Year Positions: 12
Summer Positions: 12
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: David Evans
Field of Research: Comparative Physiology
Phone Number: 392-1489
E-mail: devans@zoo.ufl.edu
Project Description: We are interested in various aspects of fish physiology, usually focused on the role of the gill in salt and water regulation in marine fishes. In the next few years we will be investigating our hypothesis that local signaling agents, such as nitric oxide, endothelin, and prostaglandins, play a role in controlling gill perfusion and active transport of salts across the gill epithelium. For more information, visit my web site: www.zoo.ufl.edu/dhefish.
Requirements: One year of biology and chemistry, but organic chemistry and upper division status are preferred.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Ira Fischler
Field of Research: Cognitive Psychology
Phone Number: 392-0601 x 228
E-mail: ifisch@ufl.edu
Project Description: As one of several projects under UF's NIMH-sponsored Center for the Study of Emotion and Attention, we conduct research on the comprehension of emotional aspects of words and sentences, as measured by the electroencephalographic (EEG) activity that is recorded during various tasks. We've found that emotiona words produce distinct patterns of EEG activity compared to nonemotional words, but that these patterns are influenced by the attentional focus during the tasks. Undergraduates have parti- cipated extensively in these studies, and two seniors are currently doing IDS research projects under my direction.
Requirements: At least the general psychology course (PSY 2013) and one more advanced course in either cognitive or sensory psychology, psychobiology, or biology.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 3
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Bradley Fletcher
Field of Research: Molecular Biology
Phone Number: 392-8558
E-mail: bsf@college.med.ufl.edu
Project Description: Our laboratory is interested in using transposons as delivery vehicles for therapeutic gene therapy. We have made significant modifications to the Sleeping Beauty transposon in order to increase its efficiency. We utilize cationic lipids or other polymers to deliver plasmid DNA to rodent models. Our emphasis is on targeting delivery to endothelial cells to treat specific conditions including hemophilia, hypertension and cancer. Additional interests in the laboratory include retroviral expression cloning.
Requirements: Basic knowledge of molecular biology and genetics. Strong commitment to, and adequate time for, research (minimum two or more semesters). Upper classmen (junior/senior) preferred, but exceptions can be made. Students majoring in IDS-Biochemistry and Microbiology and are the most appropriate people.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Bradley Fletcher
Field of Research: Molecular Biology
Phone Number: 392-8558
E-mail: bsf@pharmacology.ufl.edu
Project Description: Our laboratory is interested in using TRANSPOSONS as delivery vehicles for therapeutic GENE THERAPY. We have made significant modifications to the Sleeping Beauty transposon in order to increase its efficiency and we are testing a new transposon system called piggyBac. We utilize cationic lipids or other polymers to deliver plasmid DNA to rodent models. Our emphasis is on targeting delivery to endothelial cells to treat specific conditions including hemophilia, hypertension and cancer. Additional interests in the laboratory include retroviral expression cloning.
Requirements: Basic knowledge of molecular biology and genetics. Strong commitment to, and adequate time for, research (minimum two or more semesters). Lower classmen preferred(sophmore/junior)so adequate time can be deicated toward resech, but exceptions can be made. Students majoring in IDS-Biochemistry and Microbiology and are the most appropriate people.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 4
Summer Positions: 4
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Kevin Folta
Field of Research: Plant Molecular Bio, Physiology
Phone Number: 846-2339
E-mail: kfolta@ifas.ufl.edu
Project Description: We have two reserach tracks: 1. SIGNAL TRANSDUCTION-- My laboratory is interested in control gene expression and developmental events surrounding the transition between plant growth in darkness and growth in light. This process, photomorphogenesis, involves the coordinated activities of a number of photoreceptors and signal transduction pathways. We are using a multi-faceted approach, incorporating physiological, genomic, biochemical and genetic methods to dissect light signaling networks. Expect to learn valuable basic techniques in gene discovery, plant physiology and DNA/RNA manipulation. ***Just about all undergraduate researchers that have shown commitment to the work have found publication in peer-reviewed journals.***
Requirements: Commitment to the project is essential. We will design a project that will mesh well with your specific backgrounds and interests. Any lab experience will prove valuable, but we will train you. Preference given to students with plant science interests, especially those considering graduate training in plant biology.
Starting Date: any time
Ending Date: none
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Kevin Folta
Field of Research: Plant Genomics, Molecular Biology
Phone Number: 846-2339
E-mail: kfolta@ifas.ufl.edu
Project Description: STRAWBERRY GENOMICS - We have an ambitious program to study structural, functional and translational genomics in this important Florida crop. Our research stategy uses molecular tools to understand the basis of processes important to agriculture. We have outstanding tools to perform groundbreaking work and seek abmitious students to aid in these pursuits. Expect to learn valuable basic techniques in gene discovery, plant physiology and DNA/RNA manipulation. ***Just about all undergraduate researchers that have shown commitment to the work have found publication in peer-reviewed journals.***
Requirements: Commitment to the project is essential. We will design a project that will mesh well with your specific background and interests. Any lab experience will prove valuable, but we will train you. Preference given to students with plant science interests, especially those considering graduate training in plant biology.
Starting Date: any time
Ending Date: none
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Richard Frye
Field of Research: Neurological Basis of Learning Disabilities
Phone Number: 352-273-5778
E-mail: fryerich@peds.ufl.edu
Project Description: Learning Disabilities may affect as many as 10-15% of children. Although, educationally -based remediation can help individuals improve their skills, recent research has demonstrated that residual cognitive difficulties extend into adulthood. Despite the advances in our knowledge about the brain and behavior, the neurological basis of many Learning Disabilities is still largely unknown and controversial. The Division of Pediatric Neurology has coordinated the flagship state funded Learning Disabilities Clinic for over 20 years. This clinic is fueled by the collaboration of a multidisciplinary team that includes Education, Psychology and Neuropsychology specialists. Over the past several years we have built a research database that contains the results of our comprehensive evaluation of children with various learning problems. We also have ongoing neuroimaging experiments using magnetoencephalography (MEG) and functional MRI. We seek students with several projects including: (1) statistical modeling of data derived from our database, (2) analysis of MEG data, and (3) assisting with neuroimaging in the pediatric population.
Requirements: Depending on project, candidate may require (1) knowledge in experimental design and statistics, (2) excellent interpersonal skills and an ability to work with children, and/or (3) knowledge of neuroimaging methods.
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions:
Summer Positions: 2
Independent Study: Not Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Maria Gallo-Meagher
Field of Research: Molecular biology and tissue culture
Phone Number: 392-1823
E-mail: mgmea@ifas.ufl.edu
Project Description: To aid in investigations for the development of genetic transformation systems in peanut.
Requirements: biology major with lab experience
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Dovie Gamble
Field of Research: All Disciplines
Phone Number: 846-2575
E-mail: dgamble@ufl.edu
Project Description: The McNair Program is designed to provide undergraduates with effective preparation to enter and complete doctoral programs. Students perform research with a faculty mentor and attend seminars and workshops on topics relevant to doctoral study. Please note that the salary noted below is actually in the form of a Research Stipend.
Requirements: Low income, first generation college student and/or underrepresented minority; U.S. citizen or permanent resident; 3.0 or higher GPA
Starting Date: Fall (each year)
Ending Date: Summer A
Academic Year Positions: 30 funded
Summer Positions: Summer A only
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Not Available

Principal Investigator: Daniel Hahn
Field of Research: Diabetes and Obesity, in Insects
Phone Number: 392-1901x156
E-mail: dahahn@ifas.ufl.edu
Project Description: Our lab uses insects as models for basic physiological processes in human diseases. One current project explores how flies regulate blood sugar and fat loads in response to seasonal cycles. Flies enter a hibernation-like state during the winter; and like hibernating grizzly bears, over wintering flies accumulate greater fat stores than summer flies. We are studying the roles of two important endocrine signaling pathways in this process, insulin (yes, flies have an insulin signaling system!) and the glucagon-like adipokinetic hormone in this process.
Requirements: Student must be willing to work hard and learn new things. No experience necessary, but prior coursework in biology and chemistry a plus.
Starting Date: various
Ending Date: various
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Daniel Hahn
Field of Research: Ecology, Evolution, & Physiology
Phone Number: 392-1901x156
E-mail: dahahn@ifas.ufl.edu
Project Description: How important is size? Our lab combines techniques from a number of fields including ecology, evolutionary biology, physiology and biochemistry to determine how traits such as body size and nutritional status affect survival and reproduction in insects. Training could include a number of techniques including behavior, field collections, artificial selection, respirometry, molecular genetics/proteomics and analytical biochemistry.
Requirements: Student must be willing to work hard and learn new things. No experience necessary, but prior coursework in biology and chemistry a plus.
Starting Date: various
Ending Date: various
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: william haller
Field of Research: invasive plant management/biology/control
Phone Number: 352-392-9615
E-mail: wth@ifas.ufl.edu
Project Description: Fellow faculty and I are involved in many aspects of invasive aquatic, wetland and upland plant biology, control and ecological effects of control efforts,, fire, mechanical, chemical and biological. We are located at the Center for aquatic and invasive plants, 9 miles northwest of campus off millhopper road, so transportation will be a necessity. See our website at http:/plants.ifas.ufl.edu for more details. Research is currently (2006) bein conducted on old world climbing fern, air potato, ardisia, hydrilla, water lettuce and water hyacinth,, and even a survey of invasive duckweeds in florida.., we are even evaluating the food consumption,, ie. aquatic plant consumption of native versus exotic apple snails. Specific research includes growth and reproduction, productivity, effects of invasive plants on aquatic ecosystems and aquatic and other invasive weed control programs..The Center for Aquatic and Invasive Plants also cooperates with the World Bank in Washington, DC to place a UF undergraduate student interested in invasive species into a summer internship at the WB in DC. Socicitations for this competitive internship will be sent out in early January. Contact haller for further details.
Requirements: A willingness to work the task to the end,, and interest and enthusiasm for research and finding answers.....its not easy work and you sweat once in a while!!!
Starting Date: Anytime
Ending Date: flexible
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Nancy Hardt
Field of Research: Pathology
Phone Number: 395-0238
E-mail: hardt@pathology.ufl.edu
Project Description: Maintain extensive database of breast implant cases. Database can be used to develop avenues of inquiry according to the student's interest. Histology experience would be helpful.
Requirements: Must be capable of independent work. Histology helpful. I will teach any pathology needed. Must be facile with spreadsheet Programs. The database is currently in Quattro.
Starting Date: 1/1/97
Ending Date: ongoing
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Brian Harfe
Field of Research: Developmental Biology/Genetics
Phone Number: 352-392-1642
E-mail: bharfe@mgm.ufl.edu
Project Description: The goal of this project is to understand the molecular pathways responsible for joint formation during development. Joints form from the condensation of mesenchymal cells. Members of the TGF? superfamily have been shown to play an important role in specifying joint formation. In particular, members of the TGF? Bmp5/6/7 andGdf5/6/7 subfamilies are known to be important for joint formation. However, the role of the Bmp-2/4 subfamily has not been analyzed during joint formation since Bmp-2 and Bmp-4 null mouse embryos die before the joints form. We have created limb-specific knockouts of Bmp-2 and Bmp-4 in mice to analyze joint formation when these proteins are absent. We are also crossing these tissue-specific knockouts to additional mouse mutants known to have joint defects. This information will aid in the development of treatments for the large number of joint problems present in the human population. This project involves extensive work with mice in the SPF facility and common molecular biology techniques. Students who can commit to working in the lab for at least 12 hours a week for a year or longer are encouraged to apply. Upon completion of this project, the student will be well positioned for further research in the fields of developmental biology and genetics.
Requirements: Students should have completed basic biology classes. A working knowledge of molecular biology and genetics would be very useful. Students are expected to be in the lab at least 12 hours a week for an entire academic year. This project involves an extensive use of mice including harvesting embryos.
Starting Date: Late Spring 2004 or Summer 2004
Ending Date: Variable
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Alice Harmon
Field of Research: plant biochemistry
Phone Number: 352 273-8096
E-mail: harmon@.ufl.edu
Project Description: The goal of this project is to biochemically characterize representative members of the CDPK family. CDPKs (calcium-dependent protein kinases) are involved in sensing intracellular calcium signals and bringing about cellular responses to external stimuli. In the model plant Arabidopsis, there are 34 genes that encode CDPKs. The student will be involved in cloning cDNAs encoding CDPKs into a bacterial expression vector and expressing CDPK proteins and purifying them. The student will assist in characterization, including crossreactivity to antibodies, analysis of autophosphorylation sites by mass spectrometry, and substrate specificity tests.
Requirements: Requirements: A strong background in chemistry is required. Students who have taken or are taking biochemistry will be given preference. Students should be able to work 10-15 hours per week during Spring Semester and 20-30 hours per week in the summer of 2007. Applications from underrepresented minorities and women are encouraged.
Starting Date: January, 2007
Ending Date: August 2007
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Not Available

Principal Investigator: Mirian Hay-Roe
Field of Research: Ecology, lepidoptera biology
Phone Number: (352)846-2000 Ext 478
E-mail: mmhr@ufl.edu
Project Description: Chemical interactions between butterflies of the genus Heliconius and their hostplants Passiflora, and the implications of such interactions on the organization of natural communities and the evolution of species.
Requirements: Background in Biology, responsible, dynamic. Morning availability.
Starting Date: 09/01/06
Ending Date: N/A
Academic Year Positions: Not limited
Summer Positions: Not limited
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Jacqueline Hobbs
Field of Research: Psychiatry, Virology
Phone Number: 352-294-0412
E-mail: jahobbs@psychiatry.ufl.edu
Project Description: My laboratory is interested in the basic biology of parvovirus-brain interactions. Parvoviruses are small DNA-containing viruses. There are two parvoviruses of human concern: 1) adeno-associated virus (AAV) which is not known to cause human disease, and 2) parvovirus B19 (B19) which causes multiple human disorders from benign to life-threatening conditions. There is some clinical evidence that B19 can infect the brain and cause disease, but very little is known about this area. We are asking the questions of whether or not these viruses infect the brain and at what point in neural development is the infection most likely to occur. We are also determining what factors enhance the ability of these viruses to infect brain cells. Another area of interest in the lab is potential viral etiologies of mental illnesses such as schizophrenia, bipolar disorder, and autism. We have a large number of post-mortem human brain tissues for studies. Our studies utilize the following techniques: cell culture, polymerase chain reaction (PCR), RT-PCR, nested PCR, flow cytometry, and RNA/DNA analysis by agarose gel electrophoresis. There are a variety of projects that could be undertaken by undergraduate students.
Requirements: This position requires that the applicant pay attention to small details, be very organized and neat.
Starting Date: ongoing
Ending Date: ongoing
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Sidney Homan
Field of Research: English, Theatre
Phone Number: 352-378-9166
E-mail: shakes@ufl.edu
Project Description: I recently lost one of my two Honors research assistants because of illness and am here seeking to replace him. I am finishing a book called CHALLENGES INTHE THEATRE (about productoins that make unusual demands on directors, actors, and audience, demands beyond the normal) and need a research assistant to: 1. help prepare an anntated bibliogrpahy of recent scholarship on and productions of the several plays treted in tthe book (from Pinter's NO MAN'S LAND to Shakespeare's AS YOU LIKE IT, among others); 2. serve as a collborator, a consultant on the manuscript (translation: your opinion of the book counts!); 3. and help proof the manuscript.
Requirements: 1. facility using the internet; 2. and the library; 3. someone who enjoys the theatre and playing the role of editor
Starting Date: as soon as possible
Ending Date: could extent through spring semester
Academic Year Positions: one or two
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Jeffrey Hughes
Field of Research: Gene Therapy
Phone Number: 352-846-2725
E-mail: hughes@cop.health.ufl.edu
Project Description: My lab studies the underlying principles of macromolecule movement. We then use these finding to design better drug delivery systems. In particular, recently we have been interested in using cationic lipids to transport nucleic acids into cells in the aim of treating diseaes. In addition, we are also very interested in factors which can influence cell membranes and consequences on biological activity.
Requirements: Basic Chemsitry and Biology Courses
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Margaret James
Field of Research: Drug Metabolism
Phone Number: 352 846 1952
E-mail: mojames@ufl.edu
Project Description: Study of the effect of celecoxib on the sulfotransferase enzyme. Research in this laboratory has shown that celecoxib, an analgesic and cyclo-oxygenase 2 inhibitor, influences the biotransformation of several drugs and steroids. The project will further examine the interaction of celecoxib with drug-metabolizing enzymes.
Requirements: Chemistry or biochemistry major
Starting Date: flexible
Ending Date: flexible
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Sally Johnson
Field of Research: Cell Biology/Muscle repair
Phone Number:
E-mail: sjohnson@animal.ufl.edu
Project Description: Adult muscle stem cells, also referred to as satellite cells, reside within normal tissue in a mitotically inactive state. Upon injury or growth stimuli, the cells exit quiescence, proliferate and subsequently differentiate into the large muscle fibers responsible for contractile motion. Hepatocyte growth factor and Notch signaling pathways are crucial to the activation of myogenic stem cells. However, the events and signals necessary for return of a daughter cell to the dormant state remains largely unknown. Thus, the goal of this project is identify marker proteins that participate in cell cycle arrest in satellite cells.
Requirements: The student should have completed coursework in biology, biochemistry or molecular biology. A general working knowledge of laboratory procedure is preferred.
Starting Date: 2/1/2006
Ending Date: TBA
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: David Julian
Field of Research: Ecological physiology
Phone Number: 392-5878
E-mail: julian@zoo.ufl.edu
Project Description: The focus of my laboratory is on ecological and comparative physiology. We are currently investigating the cellular and molecular adaptations of marine and aquatic invertebrates to hypoxia, environmental toxins and other physiological stresses. The objectives of our research are twofold: first, we hope to understand how some marine invertebrates can tolerate, and even thrive, in extreme and seemingly toxic conditions, and second, we hope to clarify the cellular and molecular mechanisms by which humans and other vertebrates are affected by these same challenges. In this research, we use a variety of animal and in vitro models, including marine worms, aquatic fish, the nematode C. elegans, and mammalian neuronal and glial cell cultures. Students in my lab can learn a variety of techniques, including cell culture, molecular biology, electrophysiology, histology, electron microscopy, enzyme biochemistry and respirometry. More information is available at the lab's web site: http://www.zoology.ufl.edu/julian/
Requirements: One year each of biology and chemistry. Upper division status helpful, but not required.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: David Julian
Field of Research: Comparative and Ecological Physiology
Phone Number: 392-5878
E-mail: julian@zoo.ufl.edu
Project Description: The focus of my laboratory is on ecological and comparative physiology. We are currently investigating the cellular and molecular adaptations of marine and aquatic invertebrates to hypoxia, environmental toxins and other physiological stresses. The objectives of our research are twofold: first, we hope to understand how some marine invertebrates can tolerate, and even thrive, in extreme and seemingly toxic conditions, and second, we hope to clarify the cellular and molecular mechanisms by which humans and other vertebrates are affected by these same challenges. In this research, we use a variety of animal and in vitro models, including marine worms, aquatic fish, the nematode C. elegans, and mammalian cell cultures. Students in my lab can learn a variety of techniques, including cell culture, molecular biology, electrophysiology, histology, electron microscopy, enzyme biochemistry and respirometry. More information is available at the lab's web site: http://www.zoo.ufl.edu/julian/
Requirements: One year each of college biology and chemistry (all with an A grade). Prior research experience is not required. Sophomore or junior status preferred, but not essential.
Starting Date: Ongoing
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Michael Katovich
Field of Research: physiology
Phone Number: 392-3292
E-mail: katovich@cop.ufl.edu
Project Description: Investigate various models of experimental hypertensive rat models. Major emphasis is alterations in the renin angiotensin system and its influence on the development of hypertension and related cardiovascular complications. In vivo and in vitro measurements are made. Cell culture experiments to complement the animal experiments are also performed in the lab.
Requirements: anyone in the lab will have to undergo training through IACUC (on line) to be approved to use animals. individual should not have any allergies to rodents.
Starting Date: variable
Ending Date: variable
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Maureen Keller-Wood
Field of Research: Physiology and Pharmacology
Phone Number:
E-mail: kellerwd@cop.ufl.edu
Project Description: During pregnancy maternal physiology is altered. One of these adaptations is change in secretion of steroid hormones by the adrenal gland. Our studies suggest that these changes are crucial for both maternal health and fetal well-being. Current research interests in the lab include the effects of steroid hormones from the adrenal and placenta on the maternal brain and vasculature during pregnancy, and effects of maternal adrenal steroid secretion on fetal physiology, including effects on fetal lung, kidney, brain and heart. Potential projects would incorporate methods such as real-time PCR measurement of mRNA for target genes induced by steroid action, and Western blot and immunohistochemical analysis of the corresponding proteins.
Requirements: undergraduate level biology and chemistry including some laboratory coursework
Starting Date: Fall 2006
Ending Date:
Academic Year Positions: 2
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Soo-Jeong Kim
Field of Research: Genetics of Neurodevelopmental Disorders
Phone Number: 352-392-7322
E-mail: soojkim@ufl.edu
Project Description: We are interested in finding contributing genetic factors for specific behavioral and psychiatric phenotypes of neurodevelopmental genetic disorders. Currently, we have enlisted two clinical populations for our study: Autism Spectrum Disorder and Prader-Willi syndrome. Our project consists of clinical assessments of participating subjects (phenotypic assessment) and molecular genetic study (genotyping) to find phenotype-genotype correlations.
Requirements: Applicants interested in clinical assessments are required to have good clinical manner and motivation to learn new diagnostic assessments. Applicants interested in molecular genetic study are required to have motivation to learn new molecular genetic study protocols, such as DNA extraction, quantification, and genotyping. Strong work ethics and motivation are most important.
Starting Date: ASAP
Ending Date: NA
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Prof. F. Wayne King
Field of Research: Herpetology
Phone Number: 352 392 6573
E-mail: kaiman@flmnh.ufl.edu
Project Description: The Florida Museum of Natural History, Division of Herpetology, maintains major webpages on 'Herpetology', 'Herpetology Programs at the UF' (including courses offered in WEC, ZOO, GEO, and VME), 'Herp Faculty, Grad Students, and Alumni', 'Fieldguides to Florida Reptiles and Amphibians', 'Crocodilians', 'Crocodilians, Tuatara, and Turtle Species of the World' and other topics related to amphibians and reptiles (including thousands of pages and hundreds of images). The public accesses these pages thousands of times each day for information about reptiles and amphibians. Assistance is needed in formatting these pages and images for the web, keeping them current, checking broken links, and developing other exciting pages of interest to professional and amateur herpetologists, reptile and amphibian pet keepers, students, and the general public.
Requirements: Knowledge of webpage formatting, including html, dhtml, and/or xml; use of web page development/editing software and photo/image processing software. Though not required, a strong background in graphic arts would be an asset.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: contact faculty mentor
Summer Positions: contact faculty mentor
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Harry Klee
Field of Research: Molecular Biology
Phone Number: 392-8249
E-mail: hjklee@ifas.ufl.edu
Project Description: Our lab is working to understand the molecular mechanisms whereby the hormone ethylene acts to control plant growth and development. Ongoing projects available for independent study include gene identification, protein-protein interactions and production of transgenic plants. These projects offer opportunities to learn basic molecular biology, biochemistry and tissue culture skills. The projects are aimed at identifying the gene products involved in hormone signal transduction.
Requirements: Molecular biology and microbiology courses would be very helpful, particularly lab courses. Commitemt to and enthusiasm for science are essential.
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Christiaan Leeuwenburgh
Field of Research: Biochemistry of Aging
Phone Number: 352-392-9575 (1356)
E-mail: cleeuwen@ufl.edu
Project Description: Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. In both humans and animals, the aging process in several irreplaceable post-mitotic tissues (e.g., heart, skeletal muscle, and brain) has been associated with a decrease in the total number of cells. So a reduction in the total number of viable cells may lead to an accelerated decline in function in the heart, skeletal muscle, and brain. In addition to cell loss via apoptosis may be a major factor contributing to the loss of post-mitotic cells with age. The term apoptosis is used to describe programmed cell death, a type of cell death involved in cellular development distinct from necrosis. Generally, apoptotic cells die by design whereas necrotic cells die due to accident and lethal injury. Senescent aging likely involves both programmed changes in gene expression and 'wear and tear' mechanisms, such as oxygen radicals, mitochondrial DNA damage, and the formation of glycooxidation products also called advanced glycation end products (AGE). Programmed changes in gene expression and 'wear and tear' mechanisms are likely interlinked, and both may contribute to apoptosis. Although evidence exists that the incidence of apoptosis increases in post-mitotic cells with age, there are few studies to date that have attempted to identify the molecular mechanisms underlying the cell loss. Recent evidence suggests that mitochondria may play a key role in regulating apoptosis. With aging, the radical production by mitochondria can lead to increased oxidative stress. Oxidative stress is one of the many death-inducing signals, which can trigger mitochondria to release caspase-activating proteins such as cytochrome c and apoptosis inducing factor. In our studies, we examined the role that mitochondria play in influencing apoptosis in the heart, brain, and skeletal muscle. If the mechanisms underlying the cell loss with age can be identified, it could help explain the loss of function with age and may lead to specific therapeutic interventions that could attenuate this cell loss.
Requirements: Biochemistry and Interest in Aging Research
Starting Date: Summer 2002
Ending Date: Fall 2003
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Christiaan Leeuwenburgh
Field of Research: Biochemistry of Aging
Phone Number: 352-392-9575 (1356)
E-mail: cleeuwen@ufl.edu
Project Description: Senescent aging probably involves both programmed changes in gene expression, “wear and tear” mechanisms such as oxidative stress by oxygen radicals, mitochondrial DNA damage, the formation of glycooxidation products, and failure of repair mechanisms. Moreover, recent work suggests that mitochondria may play a key role in regulating apoptosis due to chronic life-long radical production by mitochondria leading to an increase in oxidative stress associated with mitochondrial DNA deletions, DNA damage and apoptosis. Although evidence exists that the incidence of apoptosis increases in post-mitotic cells with age, there are few studies to date that have attempted to identify the molecular mechanisms underlying this cell loss.
Requirements: Keen interest in Biochemistry and Cell Biology
Starting Date: 2004
Ending Date: 2006
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Ann Marie LeVine
Field of Research: Lung
Phone Number: 3523921189
E-mail: levineam@peds.ufl.edu
Project Description: The laboratory focuses on lung injury and repair with emphasis on the surfactant proteins and their role in host defense. The immune response of the lung to bacterial and viral infection is also under investigation.
Requirements: Enthusiastic, energetic and willing to learn There is sufficient personel in the laboratory to train and teach new molecular biology techniques
Starting Date:
Ending Date:
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Daiqing Liao
Field of Research: Cancer Biology, Molecular Cell Biology, Virology
Phone Number: 352-294-7976
E-mail: dliao@ufl.edu
Project Description: Our research program focuses on understanding function and regulation of tumor suppressor p53 and its homologous transcriptional activators by viral oncogenes and cellular proteins. In one project, we are studying how adenovirus E1B 55-kDa oncoprotein impacts on p53 pathway and roles of this viral oncoprotein in cell transformation induced by adenovirus, a DNA tumor virus. We have found that the E1B 55-kDa protein inhibits p53’s functions through several distinct biochemical mechanisms including inhibition of posttranslational modifications of p53, sequestration of p53 in the cytoplasm and impairs regulation of p53 by cellular proteins. Current efforts focus on understanding how E1B 55-kDa oncoprotein represses transcription and potential role of cytoplasmic sequestration of p53 by this viral oncogene in apoptosis. In another project, we are investigating the interplay between acetylase and coactivator PCAF and p53 family of proteins and the impact of their interactions on expression of p53 target genes and on tumor suppression. We are also interested in understanding how stresses relay signals to p53. To this end, we have found that p53 is phosphorylated at specific serine residues in the C-terminal regulatory domain by a yet to be identified kinase. We are making progress in identify this kinase through proteomic approaches. Our goal here is to identify this kinase and study its role in signaling pathways converging on p53. Finally, we have been interested in understanding the interactions between p53 family proteins and Daxx. We and others have found that Daxx binds to p53 and p73. These interactions may play important roles in the diverse functions of Daxx ranging from transcriptional regulation to apoptosis, as well as cell cycle control. Our long-term goal is to understand the cellular regulatory circuitries that govern cell growth and transformation through focused research on the p53 pathway by using cutting-edge technologies in cell biology, genomics and proteomics. We believe that such approaches will likely yield useful knowledge that will have major impact in cancer cell biology and may also have translational values in designing treatments for cancer patients. See: http://plaza.ufl.edu/dliao/
Requirements:
Starting Date: Open
Ending Date: Felxible
Academic Year Positions:
Summer Positions: Two
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Sally Litherland
Field of Research: Immunology
Phone Number: 352 392-5169
E-mail: litherla@pathology.ufl.edu
Project Description: Analysis of Signal transduction dysregulation in autoimmune diseases.
Requirements: Interest in medically applicable research; chemistry & biological sciences coursework, hepatitis B & tetanus vaccinations.
Starting Date: open
Ending Date: open
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Bin Liu
Field of Research: Neurodegenerative diseases
Phone Number: 352 392-3972
E-mail: bliu12@ufl.edu
Project Description: Neurodegenerative diseases such as Parkinson's and Alzheimer's disease remain a major challenge in our search for a causative factor and cure. With an increasingly aging population, it is ever more urgent to gain a better understanding of the disease process. The focus of this laboratory is two-fold. First, we investigate the effect of exposure to environmental toxins on the development of Parkinson’s disease. Second, deciphering the mechanism responsible for the neurodegenerative process offers us unique targets for designing novel therapeutic approaches for the treatment of the disease. Neural cell culture and rodent models are used in our studies. Techniques routinely used in the laboratory include cell culture, establishment of primary cultures, enzyme activity, protein analysis, Western blot, immunostaining, neuronal function assays, cytokine analysis, and free radical determination.
Requirements: Basic chemistry and biology
Starting Date: Open
Ending Date: Ongoing
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Chen Liu
Field of Research: Immunology, Vriology, and Genetics
Phone Number: 352-273-5413
E-mail: liu@pathology.ufl.edu
Project Description: There three research areas in my laboratory: 1. Immunology and Virology of Hepatitis C Virus. We are interested in the mechanisms of viral replication, antiviral agents, innate and adaptive immunity, and vaccine development; 2. Oncogenes and Cancer. We are interested in oncogene mutation analysis of patient cancer tissues; 3. Alpha-1 antitrypsin deficiency and Liver disease. We are interested in finding therapeutic molecules to treat this genetic disease.
Requirements: Biology or science-related major.
Starting Date: Flexible
Ending Date: flexible
Academic Year Positions: flexible
Summer Positions: flexible
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Joanna Long
Field of Research: Biochemistry & Molecular Biology
Phone Number: x6-1506
E-mail: jrlong@mbi.ufl.edu
Project Description: Multiple projects examining protein structure and function in lipid membranes and extracellular matrices. Use of molecular biology or solid phase peptide synthesis for protein expression, biophysical characterization techniques, spectroscopy, computer modeling. Projects: 1) Ion channel function in heterogeneous membranes, 2) Mechanism of lung surfactant protein B, 3) Bone Sialoprotein and biomineralization, 4) Integrin association in membranes. Preference given to students in their second year at UF.
Requirements: Basic knowledge of biology, chemistry and molecular; undergraduate organic chemistry or microbiology lab preferred.
Starting Date: open
Ending Date: open
Academic Year Positions: 1-2
Summer Positions: 1-2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Thomas H. Mareci, Ph.D.
Field of Research: Biophysics and Biochemistry
Phone Number: 392-3375 or 392-2332
E-mail: thmareci@ufl.edu
Project Description: Our research focuses on the study of fundamental questions of tissue structure and biochemical processes in living systems accessible to study with nuclear magnetic resonance (NMR) techniques. To provide a detailed understanding of the living system, we are examining excised tissue with MR microscopy and spectroscopies then these measurements are extended to studies in vivo. This work involves a detailed investigation of biophysical processes at the cellular and molecular level along with the development of NMR measurement and processing methods, and specialized hardware. Our current projects are the following: 1) We are studying blood-spinal-cord barrier and blood-brain-barrier disruption, using dynamic contrast enhanced MR imaging in vivo, following trauma. As part of the study, we are modeling the kinetics of lesion enhancement in a longitudinal study of barrier disruption over weeks. 2) Also we are using diffusion tensor imaging to map fiber tracts in highly structured white matter in nervous tissue and have recently extended this procedure to allow fiber tracking in the gray matter of the spinal cord. 3) We are constructing unique RF coils for implantation near the region of interest. These chronically implanted coils are inductively coupled to an external coil during measurements and provide a gain as large as a factor of 4 in signal-to-noise ratio. Because of the gains possible, these coils allow the acquisition of very spatial resolution MR images and spectra.
Requirements: Undergraduate chemistry and physics (with calculus)
Starting Date: open
Ending Date: ongoing
Academic Year Positions: one
Summer Positions: one
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Andre, P. Mauderli
Field of Research: Neural mechanisms of pain
Phone Number: 352-392-9538
E-mail: AMauderli@dental.ufl.edu
Project Description: The research is conducted in human participants and focuses on how chronic pain diseases, such as fibromyalgia syndrome, irritable bowel syndrome, myofascial pain syndrome, and traumatic brain injury affect pain sensitivity, pain modulation and the relative unpleasantness of pain. The response properties of the neural mechanisms that mediate pain are probed with thermal stimuli, and the participants rate the sensation elicited by the stimuli on a visual analog scale.
Requirements: The applicant must be interested in neural mechanisms of pain, communicate well with our study participants and be willing to spend time in the lab on a regular basis. Computer skills are advantageous.
Starting Date: anytime
Ending Date: anytime
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Julie Maupin-Furlow
Field of Research: Microbiology
Phone Number: 352-392-4095
E-mail: jmaupin@ufl.edu
Project Description: Structure and Function of Archaeal Proteases. Archaea are a metabolically diverse group of bacteria, many of which survive in extreme environmental conditions such as hydrothermal vents and the Dead Sea. The main objective of this study is to determine how the archaea use proteases in global regulatory networks to maintain quality control of proteins for survival. To achieve this objective we are using genetic, molecular, and biochemical methods. Thermophilic Gram-positive Biocatalysts for Biomass Conversion to Ethanol Escherichia coli and other Gram-negative bacteria have been genetically modified to produce ethanol efficiently from biomass using the pyruvate decarboxylase and alcohol dehydrogenase genes from Zymomonas mobilis. However, Gram-positive bacteria are hardier at high temperature and low pH and, thus, more economical for the metabolic engineering of industrial-scale ethanol production. The main objective of this study is to engineer a homo-ethanol pathway into thermophilic Gram-positive bacteria.
Requirements: Basic knowledge of microbiology. Strong commitment to and adequate time for a research experience (2 semesters commitment is desirable).
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Julie Maupin-Furlow
Field of Research: Microbiology
Phone Number: 352-392-4095
E-mail: jmaupin@ufl.edu
Project Description: I. Structure and Function of Archaeal Proteases. Archaea are a metabolically diverse group of bacteria, many of which survive in extreme environmental conditions such as hydrothermal vents and the Dead Sea. The main objective of this study is to determine how the archaea use proteases in global regulatory networks to maintain quality control of proteins for survival. To achieve this objective we are using genetic, molecular, and biochemical methods. II. Thermophilic Gram-positive Biocatalysts for Biomass Conversion to Ethanol. Escherichia coli and other Gram-negative bacteria have been genetically modified to produce ethanol efficiently from biomass using the pyruvate decarboxylase and alcohol dehydrogenase genes from Zymomonas mobilis. However, Gram-positive bacteria are hardier at high temperature and low pH and, thus, more economical for the metabolic engineering of industrial-scale ethanol production. The main objective of this study is to engineer a homo-ethanol pathway into thermophilic Gram-positive bacteria.
Requirements: Basic knowledge of microbiology. Strong commitment to and adequate time for a research experience (2 semesters commitment is desirable).
Starting Date: open
Ending Date: ongoing
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Paul Mislevy
Field of Research: Agronomey
Phone Number: 863-735-1314
E-mail: pmislevy@mail.ifas.ufl.edu
Project Description: Project ONA-03726 Title: Evaluation of Forage Gemplasm and Forage Management Practices. Evaluate promising forage plant germplasm for adaptaion, persistence, forage yield, qualily, seed production, responce to clipping or grazing management, herbicides etc.
Requirements: Research is conducted at the UF Range Cattle Research and Education Center, Ona, Florida. This center is located 180 miles south of Gainesville. Therefore applicants will need to live on the center or in a nearby town and have an automobile for transportation. This project requires applicants to work entirely in the field conducting applied research cutting plants, moving cattle from pasture to pasture etc. This would lend itself best for summer employment.
Starting Date: May 15, 2003
Ending Date: September 1, 2002
Academic Year Positions: 0
Summer Positions: 1
Independent Study: Not Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Laurence Morel
Field of Research: Immunogenetics
Phone Number: 392-2676
E-mail: morel@pathology.ufl.edu
Project Description: To characterize the genetic contribution of various chromosomal regions to Systemic Lupus Erythematosus (SLE) in a mouse model. Our research combines various techniques of molecular genetics and immunology to correlate the presentation of various autoimmune abnormalities with specific genetic backgrounds generated through selective mouse breeding.
Requirements: A strong commitment to research and some background in molecular biology and/or immunology.
Starting Date: any
Ending Date: any
Academic Year Positions: 1-2
Summer Positions:
Independent Study: Available
Work Study: Not Available
Salary: Available
Volunteer: Available

Principal Investigator: Connie Mulligan
Field of Research: Human molecular genetics
Phone Number: 392-2253, x 248
E-mail: mulligan@anthro.ufl.edu
Project Description: Genetic variants that are associated with alcohol dependence and related disorders or effects such as binging, flushing, or antisocial personality disorder are being investigated. Questions of interest include the use of recent methods to detect variants with small effect on the disease and the relationship between the presumed protective effect of flushing and prevalence of alcohol dependence. Assayed variants occur in alcohol metabolism genes (ADH, ALDH) and neurological response genes (opioid, seratonin, and dopamine receptors). Native Americans suffer a disproportionately high rate of alcohol dependence relative to other U.S. populations and several populations have agreed to participate in our study.
Requirements: Strong commitment to and adequate time for a research experience (at least 2 semesters commitment is desirable). Some basic lab experience is required and knowledge of PCR and agarose gel electrophoresis is a plus.
Starting Date: Open
Ending Date: Open
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Required
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Connie Mulligan
Field of Research: Human molecular genetics
Phone Number: 392-2253, x 248
E-mail: mulligan@anthro.ufl.edu
Project Description: We are analyzing molecular genetic variation in human populations located throughout the Horn of Africa and the Arabian peninsula to test hypotheses concerning migrations across the Red Sea and the evolution of language and food production methods. This region of the world is known to be important for the emergence of anatomically modern humans, but it is also important for more recent evolution. We are interested in determining the origin and directionality of migrations across the Red Sea and the evolution of the Afro-Asiatic language family. Mitochondrial, X and Y, and autosomal genes and variants are assayed in order to address these questions. Specific regions of interest include Ethiopia, Eritrea, Oman and Yemen. Additional countries will be included as the project develops.
Requirements: Strong commitment to and adequate time for a research experience (at least 2 semesters commitment is desirable). Some basic lab experience is required and knowledge of PCR and agarose gel electrophoresis is a plus.
Starting Date: Open
Ending Date: Open
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Required
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Josef Neu, M.D.
Field of Research: Neonatal Nutritional Biochemistry and Developmental Gastroenterology
Phone Number: 392-4195
E-mail: neuj@peds.ufl.edu
Project Description: Nutrition and the GI environment in the neonate have major effects not only during infancy, but for the entire lifetime of the individual, and this can even span generations due to epigenetic effects. Our lab has several ongoing projects that involve the requirements for certain amino acids such as glutamine and arginine in very low birthweight infants, the effect of various nutrients on subsequent development of Type 1 and Type 2 diabetes, the effect of the intestinal commnensal microflora and probiotics on intestinal development, and the effects of novel nutritional agents on retinal diseases such as retinopathy of prematurity. Our work spans from evaluation of basic mechanisms of nutrients in cell cultures, studies in animal models and translation of these to and from studies in human infants.
Requirements: Strong science background. Biochemistry course and some lab experience very helpful.
Starting Date: open ended
Ending Date: open ended
Academic Year Positions: Yes
Summer Positions: Yes
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Harry S. Nick
Field of Research: Biochemistry and Molecular Biology
Phone Number: 392-3303
E-mail: hnick@ufl.edu
Project Description: Our laboratory's research focuses on understanding how mammalian genes are turned on and off by cell and tissue-specific mechanisms. We utilize advanced techniques in molecular biology to study molecular mechanisms which control how genes are regulated, by understanding the organization of chromatin structure and studying protein-DNA interactions. Research has focused on proteins that exhibit both pro- and anti-inflammatory activities in the lung, spinal cord, kidney, and intestine. These genes include: manganese superoxide dismutase (MnSOD), a potent cyto protective anti-oxidant protein; the inducible nitric oxide synthase (iNOS) gene which generates elevated levels of the powerful neurotransmitter and vasodilator, nitric oxide (NO); cytoplasmic phospholipase A2 (cPLA2) which controls intracellular levels of arachidonate metabolites and heme oxygenase, the enzyme responsible for heme degradation and the sole source of the signal molecule, carbon monoxide. These genes are also linked through transcriptional regulation by a subset of pro-inflammatory mediators, including bacterial endotoxin (LPS), interleukin 1 (IL-1), tumor necrosis factor (TNF-alpha) and interferon-gamma as well as a variety of cellular stress signals. The ultimate goals are to understand the mechanisms controlling gene regulation in an effort to modulate gene expression patterns to develop therapeutic strategies that affect outcome in appropriate disease pathologies.
Requirements: Undergraduate Biology minimum, some knowledge of molecular biology preferred
Starting Date: open
Ending Date: open
Academic Year Positions: 1-2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Prof. Max Nickerson
Field of Research: Herpetology
Phone Number: 352 392 6581
E-mail: maxn@flmnh.ufl.edu
Project Description: The Florida Museum of Natural History's Division of Herpetology maintains major archival research collections of preserved amphibians and reptiles that provide a regional base for research on systematic biology of these species, their morphology, ecology, behavior, distribution and conservation. Assistance is needed in cataloguing, sorting, and labelling specimens, in arranging the collections on the shelves, and in classifying the reprint library.
Requirements: An interest in reptiles, amphibians, wildlife, zoology, biology, natural history, systematics, taxonomy, biological diversity, wild species, or environmental science. Though not required, Library Sciences skills would be an asset.
Starting Date: 1 September 1999
Ending Date: ongoing
Academic Year Positions: Variable
Summer Positions: Variable
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Required

Principal Investigator: Juan C Nino
Field of Research: Materials Science and Engineering
Phone Number: 352-846-3787
E-mail: jnino@mse.ufl.edu
Project Description: BIOCERAMIC SCAFFOLDS FOR TISSUE ENGINEERING- Bone diseases and injuries are serious conditions that have a significant impact on the quality of life of an individual. Most of the materials used today have too many disadvantages and can still be much improved. he objective of this proposal is to develop of a new class of bioactive ceramics with good mechanical properties by investigating the bioactivity and mechanical properties of selected pyrochlore compositions.
Requirements:
Starting Date:
Ending Date:
Academic Year Positions:
Summer Positions:
Independent Study: Not Available
Work Study: Not Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Lucia Notterpek
Field of Research: Inherited peripheral neurodegeneration
Phone Number: 294-0030
E-mail: notterp@mbi.ufl.edu
Project Description: The overall interests of the laboratory are the cellular interactions of neurons and glia during the development of the nervous system and how these processes are altered in disease. A key element for normal neuronal functioning is myelination, the glial ensheathment of axonal processes that serves to facilitate signal propagation from the neuronal cell body to the synaptic terminal. A glial molecule, termed PMP22, has been shown to have a key role in normal nerve development, since point mutations, deletions or duplications of the PMP22 gene are associated with nerve degeneration and disease. It is the main goal of my laboratory to define the roles of PMP22 in the peripheral nervous system and in the pathogenesis of neuromuscular disorders. Various in vivo and in vitro model systems are available in the laboratory to examine how alterations in PMP22 gene expression lead to abnormal myelination and subsequent axonal degeneration.
Requirements: Strong interest in basic biomedical research.
Starting Date: open
Ending Date: open
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Thomas O'Brien
Field of Research:
Phone Number: 392-6878
E-mail: tobrien@ufl.edu, http://www.med.ufl.edu/biochem/tobrien/index.html
Project Description: Our studies have shown that mammalian mitochondria contain unusual ribosomes that differ structurally and functionally from other ribosomes. These ribosomes are products of two separate genomes, and they appear to be evolving more rapidly than other ribosomes. We are using affinity probes, immunologic, and biochemical approaches to study their organization and unique functional properties. Available projects include: 1) Molecular cloning of cDNA and genes for mammalian mitochondrial ribosomal proteins; 2) Computer analysis of protein sequence, structure and evolution; 3) Computer modeling of ribosomal structure (RNA and proteins); 4) Function of GTP-binding protein; enzymatic studies.
Requirements:
Starting Date: current
Ending Date: ongoing
Academic Year Positions: 2-3
Summer Positions: 2-3
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: David Oppenheimer
Field of Research: Plant Cell Biology
Phone Number: 352-273-8105
E-mail: doppen@botany.ufl.edu
Project Description: REGULATION OF ACTIN ORGANIZATION IN PLANTS This project focuses on the newly discovered RAP proteins in plants. RAP proteins control actin organization by interacting with Actin Depolymerizing Factor (ADF), a key regulator of actin dynamics. As part of an interdisciplinary approach to the function of RAPs, we are using genetics (mutant isolation), molecular biology (gene cloning), biochemistry (in vitro protein expression), and cell biology (confocal microscopy) methods. Most of this work is carried out using the plant, Arabidopsis thaliana, because the complete genome sequence is available and insertion mutants exist for a large fraction of the known genes. The immediate goal of this project is to determine the interactions between specific RAP and ADF family members using genetic and biochemical assays.
Requirements: Undergraduate biology and chemistry
Starting Date: continuing
Ending Date:
Academic Year Positions: 2
Summer Positions: 1
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Not Available

Principal Investigator: Larry Page
Field of Research: Ichthyology
Phone Number: 392-1721, ext. 483
E-mail: lpage1@ufl.edu
Project Description: The Ichthyology Division of the Florida Museum of Natural History has several ongoing research projects on freshwater fishes, including an inventory of catfishes of the world, and geographic variation and evolutionary relationships among several taxonomic groups. Opportunities to participate in one or more of these research projects are available to undergraduates majoring in, or otherwise particularly interested in, biology.
Requirements: Requirements: Students majoring in, or otherwise particularly interested in, biology should contact Larry Page for an interview.
Starting Date: open
Ending Date: open
Academic Year Positions: 2
Summer Positions: 2
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Linda Papa
Field of Research: Clinical/ Medical
Phone Number: (352) 265-5911
E-mail: lpstat@aol.com
Project Description: Background: Each year, emergency departments treat a million adults with “minor head injury”. About 6% of these patients have some acute injury on computed tomography (CT scan) and 0.5% have an injury requiring surgery. Objectives: To compare and assess the accuracy of 2 clinical decision guidelines (the Canadian CT Head Rule and the the New Orleans criteria) for predicting ‘need for neurological intervention’ and for detecting ‘clinically important brain injury’ on CT. Importance: This clinical study of mild traumatic brain injured patients is an essential step in the development of an accurate, reliable, and clinically sensible decision rule for physicians to use. These CT Head Rules will permit physicians to standardize care of these patients and diminish the risk of missing serious injuries.
Requirements: Knowledge of some medical terminology. Medical background helpful but not necessary. Motivated and willing to learn. Study ongoing in Gainesville and Jacksonville.
Starting Date: variable
Ending Date: variable
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Linda Papa
Field of Research: Clinical/ Medical
Phone Number: (352) 265-5911
E-mail: lpstat@aol.com
Project Description: Cognitive Outcome Predictors in the Emergency Department for Mild Traumatic Brain Injury (TBI) Background: Mild TBI has been termed the 'silent epidemic' of our times. Since most patients manifest no gross neurological disturbance at the time of their injury it is difficult to predict who will develop complications. Objectives: This study will prospectively determine the incidence of cognitive and social dysfunction after mild TBI and predict which patients will develop cognitive and social function deficits after injury so that early follow-up and treatment could be instituted.
Requirements: Knowledge of some medical terminology. Motivated and willing to learn. Medical background helpful but not necessary.
Starting Date: variable
Ending Date: variable
Academic Year Positions: variable
Summer Positions: variable
Independent Study: Available
Work Study: Available
Salary: Available
Volunteer: Available

Principal Investigator: Susan Percival
Field of Research: Nutritional Sciences
Phone Number: 392-1991
E-mail: percival@ufl.edu
Project Description: This laboratory studies dietary factors that influence the immune system and inhibit carcinogenesis. Our research uses cell culture, mice and humans to investigate the mechanisms by which dietary factors such as phytochemicals in grape and grape products, mango, guava and passionfruit enhance or suppress immunity and inhibit the process of cancer.
Requirements: Completion of organic chemistry series and lab. Analytical chemistry preferred. Nutritional Sciences student preferred.
Starting Date: none
Ending Date: none
Academic Year Positions: varies
Summer Positions: varies
Independent Study: Available
Work Study: Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Deidre Pereira
Field of Research: Health Psychology
Phone Number:
E-mail: dpereira@phhp.ufl.ed
Project Description: This project examines relations among psychosocial factors, heat shock protein (HSP) 70, and cytokines in women with early stage endometrial cancer.
Requirements: Required: Introduction to Psychology Preferred: Research Methods and Statistics (or similar course)
Starting Date: 01/01/2004
Ending Date: 12/31/2004
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: Deidre Pereira
Field of Research: Health Psychology
Phone Number:
E-mail: dpereira@phhp.ufl.edu
Project Description: This project examines relations among psychosocial factors, heat shock protein (HSP) 70, and cytokines in women with early stage endometrial cancer.
Requirements: Required: Introduction to Psychology Preferred: Research Methods and Statistics (or similar course)
Starting Date: 01/01/2004
Ending Date: 12/31/2004
Academic Year Positions: 1
Summer Positions: 1
Independent Study: Available
Work Study: Not Available
Salary: Not Available
Volunteer: Available

Principal Investigator: William Perlstein
Field of Research: Clinical-Cognitive Neuroscience
Phone Number: 265-0680 x 46846
E-mail: wmp@grove.ufl.edu